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Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications

The advancement of biomedicine in a socioeconomically sustainable manner while achieving efficient patient-care is imperative to the health and well-being of society. Magnetic systems consisting of iron based nanosized components have gained prominence among researchers in a multitude of biomedical...

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Detalles Bibliográficos
Autores principales: Bossmann, Stefan H., Payne, Macy M., Kalita, Mausam, Bristow, Reece M. D., Afshar, Ayda, Perera, Ayomi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607318/
https://www.ncbi.nlm.nih.gov/pubmed/36297529
http://dx.doi.org/10.3390/pharmaceutics14102093
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author Bossmann, Stefan H.
Payne, Macy M.
Kalita, Mausam
Bristow, Reece M. D.
Afshar, Ayda
Perera, Ayomi S.
author_facet Bossmann, Stefan H.
Payne, Macy M.
Kalita, Mausam
Bristow, Reece M. D.
Afshar, Ayda
Perera, Ayomi S.
author_sort Bossmann, Stefan H.
collection PubMed
description The advancement of biomedicine in a socioeconomically sustainable manner while achieving efficient patient-care is imperative to the health and well-being of society. Magnetic systems consisting of iron based nanosized components have gained prominence among researchers in a multitude of biomedical applications. This review focuses on recent trends in the areas of diagnostic imaging and drug delivery that have benefited from iron-incorporated nanosystems, especially in cancer treatment, diagnosis and wound care applications. Discussion on imaging will emphasise on developments in MRI technology and hyperthermia based diagnosis, while advanced material synthesis and targeted, triggered transport will be the focus for drug delivery. Insights onto the challenges in transforming these technologies into day-to-day applications will also be explored with perceptions onto potential for patient-centred healthcare.
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spelling pubmed-96073182022-10-28 Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications Bossmann, Stefan H. Payne, Macy M. Kalita, Mausam Bristow, Reece M. D. Afshar, Ayda Perera, Ayomi S. Pharmaceutics Review The advancement of biomedicine in a socioeconomically sustainable manner while achieving efficient patient-care is imperative to the health and well-being of society. Magnetic systems consisting of iron based nanosized components have gained prominence among researchers in a multitude of biomedical applications. This review focuses on recent trends in the areas of diagnostic imaging and drug delivery that have benefited from iron-incorporated nanosystems, especially in cancer treatment, diagnosis and wound care applications. Discussion on imaging will emphasise on developments in MRI technology and hyperthermia based diagnosis, while advanced material synthesis and targeted, triggered transport will be the focus for drug delivery. Insights onto the challenges in transforming these technologies into day-to-day applications will also be explored with perceptions onto potential for patient-centred healthcare. MDPI 2022-09-30 /pmc/articles/PMC9607318/ /pubmed/36297529 http://dx.doi.org/10.3390/pharmaceutics14102093 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bossmann, Stefan H.
Payne, Macy M.
Kalita, Mausam
Bristow, Reece M. D.
Afshar, Ayda
Perera, Ayomi S.
Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications
title Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications
title_full Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications
title_fullStr Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications
title_full_unstemmed Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications
title_short Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications
title_sort iron-based magnetic nanosystems for diagnostic imaging and drug delivery: towards transformative biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607318/
https://www.ncbi.nlm.nih.gov/pubmed/36297529
http://dx.doi.org/10.3390/pharmaceutics14102093
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