Cargando…
Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis
There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using different diagnostic criteria, on all-cause, cardiovascular disease (CVD), and cancer mortality in older adults. In this p...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607321/ https://www.ncbi.nlm.nih.gov/pubmed/36296999 http://dx.doi.org/10.3390/nu14204315 |
_version_ | 1784818514117263360 |
---|---|
author | Moura, Letícia de Almeida Nogueira e Pagotto, Valéria Camargo Pereira, Cristina de Oliveira, Cesar Silveira, Erika Aparecida |
author_facet | Moura, Letícia de Almeida Nogueira e Pagotto, Valéria Camargo Pereira, Cristina de Oliveira, Cesar Silveira, Erika Aparecida |
author_sort | Moura, Letícia de Almeida Nogueira e |
collection | PubMed |
description | There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using different diagnostic criteria, on all-cause, cardiovascular disease (CVD), and cancer mortality in older adults. In this prospective cohort study of older adults (≥60 years), sociodemographic, lifestyle, clinical history, laboratory test, and anthropometric data were analyzed. The considered were used for AO diagnostic: waist circumference (WC) of ≥88 cm for women and ≥102 cm for men; WC of ≥77.8 cm for women and ≥98.8 cm for men; and increased waist-to-hip ratio (WHR), being the highest tertile of distribution by sex. Multivariate Cox regression and Kaplan–Meier analyses were performed. A total of 418 individuals, with an average age of 70.69 ± 7.13 years, participated in the study. In the analysis adjusted for sex and age, WHR was associated with a high risk of all-cause mortality (p = 0.044). Both cutoff points used for the WC were associated with an increased CVD mortality risk. None of the AO parameters were associated with cancer mortality. An increased WHR was associated to a higher all-cause mortality risk factor, while an increased WC was a risk factor for a higher CVD mortality in older adults. |
format | Online Article Text |
id | pubmed-9607321 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96073212022-10-28 Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis Moura, Letícia de Almeida Nogueira e Pagotto, Valéria Camargo Pereira, Cristina de Oliveira, Cesar Silveira, Erika Aparecida Nutrients Article There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using different diagnostic criteria, on all-cause, cardiovascular disease (CVD), and cancer mortality in older adults. In this prospective cohort study of older adults (≥60 years), sociodemographic, lifestyle, clinical history, laboratory test, and anthropometric data were analyzed. The considered were used for AO diagnostic: waist circumference (WC) of ≥88 cm for women and ≥102 cm for men; WC of ≥77.8 cm for women and ≥98.8 cm for men; and increased waist-to-hip ratio (WHR), being the highest tertile of distribution by sex. Multivariate Cox regression and Kaplan–Meier analyses were performed. A total of 418 individuals, with an average age of 70.69 ± 7.13 years, participated in the study. In the analysis adjusted for sex and age, WHR was associated with a high risk of all-cause mortality (p = 0.044). Both cutoff points used for the WC were associated with an increased CVD mortality risk. None of the AO parameters were associated with cancer mortality. An increased WHR was associated to a higher all-cause mortality risk factor, while an increased WC was a risk factor for a higher CVD mortality in older adults. MDPI 2022-10-15 /pmc/articles/PMC9607321/ /pubmed/36296999 http://dx.doi.org/10.3390/nu14204315 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Moura, Letícia de Almeida Nogueira e Pagotto, Valéria Camargo Pereira, Cristina de Oliveira, Cesar Silveira, Erika Aparecida Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis |
title | Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis |
title_full | Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis |
title_fullStr | Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis |
title_full_unstemmed | Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis |
title_short | Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis |
title_sort | does abdominal obesity increase all-cause, cardiovascular disease, and cancer mortality risks in older adults? a 10-year follow-up analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607321/ https://www.ncbi.nlm.nih.gov/pubmed/36296999 http://dx.doi.org/10.3390/nu14204315 |
work_keys_str_mv | AT mouraleticiadealmeidanogueirae doesabdominalobesityincreaseallcausecardiovasculardiseaseandcancermortalityrisksinolderadultsa10yearfollowupanalysis AT pagottovaleria doesabdominalobesityincreaseallcausecardiovasculardiseaseandcancermortalityrisksinolderadultsa10yearfollowupanalysis AT camargopereiracristina doesabdominalobesityincreaseallcausecardiovasculardiseaseandcancermortalityrisksinolderadultsa10yearfollowupanalysis AT deoliveiracesar doesabdominalobesityincreaseallcausecardiovasculardiseaseandcancermortalityrisksinolderadultsa10yearfollowupanalysis AT silveiraerikaaparecida doesabdominalobesityincreaseallcausecardiovasculardiseaseandcancermortalityrisksinolderadultsa10yearfollowupanalysis |