Cell Cycle Arrest and Apoptosis-Inducing Ability of Benzimidazole Derivatives: Design, Synthesis, Docking, and Biological Evaluation

In the current study, new benzimidazole-based 1,3,4-oxadiazole derivatives have been synthesized and characterized by NMR, IR, MS, and elemental analysis. The final compounds were screened for cytotoxicity against MDA-MB-231, SKOV3, and A549 cell lines and EGFR for inhibitory activities. Compounds 1...

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Detalles Bibliográficos
Autores principales: Nazreen, Syed, Almalki, Abdulraheem S. A., Elbehairi, Serag Eldin I., Shati, Ali A., Alfaifi, Mohammad Y., Elhenawy, Ahmed A., Alsenani, Nawaf I., Alfarsi, Anas, Alhadhrami, Abdulrahman, Alqurashi, Esam A., Alam, Mohammad Mahboob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607330/
https://www.ncbi.nlm.nih.gov/pubmed/36296495
http://dx.doi.org/10.3390/molecules27206899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607330/
https://www.ncbi.nlm.nih.gov/pubmed/36296495
http://dx.doi.org/10.3390/molecules27206899

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