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Microfluidic Gas Sensors: Detection Principle and Applications

With the rapid growth of emerging point-of-use (POU)/point-of-care (POC) detection technologies, miniaturized sensors for the real-time detection of gases and airborne pathogens have become essential to fight pollution, emerging contaminants, and pandemics. However, the low-cost development of minia...

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Autores principales: Kaaliveetil, Sreerag, Yang, Juliana, Alssaidy, Saud, Li, Zhenglong, Cheng, Yu-Hsuan, Menon, Niranjan Haridas, Chande, Charmi, Basuray, Sagnik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607434/
https://www.ncbi.nlm.nih.gov/pubmed/36296069
http://dx.doi.org/10.3390/mi13101716
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author Kaaliveetil, Sreerag
Yang, Juliana
Alssaidy, Saud
Li, Zhenglong
Cheng, Yu-Hsuan
Menon, Niranjan Haridas
Chande, Charmi
Basuray, Sagnik
author_facet Kaaliveetil, Sreerag
Yang, Juliana
Alssaidy, Saud
Li, Zhenglong
Cheng, Yu-Hsuan
Menon, Niranjan Haridas
Chande, Charmi
Basuray, Sagnik
author_sort Kaaliveetil, Sreerag
collection PubMed
description With the rapid growth of emerging point-of-use (POU)/point-of-care (POC) detection technologies, miniaturized sensors for the real-time detection of gases and airborne pathogens have become essential to fight pollution, emerging contaminants, and pandemics. However, the low-cost development of miniaturized gas sensors without compromising selectivity, sensitivity, and response time remains challenging. Microfluidics is a promising technology that has been exploited for decades to overcome such limitations, making it an excellent candidate for POU/POC. However, microfluidic-based gas sensors remain a nascent field. In this review, the evolution of microfluidic gas sensors from basic electronic techniques to more advanced optical techniques such as surface-enhanced Raman spectroscopy to detect analytes is documented in detail. This paper focuses on the various detection methodologies used in microfluidic-based devices for detecting gases and airborne pathogens. Non-continuous microfluidic devices such as bubble/droplet-based microfluidics technology that have been employed to detect gases and airborne pathogens are also discussed. The selectivity, sensitivity, advantages/disadvantages vis-a-vis response time, and fabrication costs for all the microfluidic sensors are tabulated. The microfluidic sensors are grouped based on the target moiety, such as air pollutants such as carbon monoxide and nitrogen oxides, and airborne pathogens such as E. coli and SARS-CoV-2. The possible application scenarios for the various microfluidic devices are critically examined.
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spelling pubmed-96074342022-10-28 Microfluidic Gas Sensors: Detection Principle and Applications Kaaliveetil, Sreerag Yang, Juliana Alssaidy, Saud Li, Zhenglong Cheng, Yu-Hsuan Menon, Niranjan Haridas Chande, Charmi Basuray, Sagnik Micromachines (Basel) Review With the rapid growth of emerging point-of-use (POU)/point-of-care (POC) detection technologies, miniaturized sensors for the real-time detection of gases and airborne pathogens have become essential to fight pollution, emerging contaminants, and pandemics. However, the low-cost development of miniaturized gas sensors without compromising selectivity, sensitivity, and response time remains challenging. Microfluidics is a promising technology that has been exploited for decades to overcome such limitations, making it an excellent candidate for POU/POC. However, microfluidic-based gas sensors remain a nascent field. In this review, the evolution of microfluidic gas sensors from basic electronic techniques to more advanced optical techniques such as surface-enhanced Raman spectroscopy to detect analytes is documented in detail. This paper focuses on the various detection methodologies used in microfluidic-based devices for detecting gases and airborne pathogens. Non-continuous microfluidic devices such as bubble/droplet-based microfluidics technology that have been employed to detect gases and airborne pathogens are also discussed. The selectivity, sensitivity, advantages/disadvantages vis-a-vis response time, and fabrication costs for all the microfluidic sensors are tabulated. The microfluidic sensors are grouped based on the target moiety, such as air pollutants such as carbon monoxide and nitrogen oxides, and airborne pathogens such as E. coli and SARS-CoV-2. The possible application scenarios for the various microfluidic devices are critically examined. MDPI 2022-10-11 /pmc/articles/PMC9607434/ /pubmed/36296069 http://dx.doi.org/10.3390/mi13101716 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kaaliveetil, Sreerag
Yang, Juliana
Alssaidy, Saud
Li, Zhenglong
Cheng, Yu-Hsuan
Menon, Niranjan Haridas
Chande, Charmi
Basuray, Sagnik
Microfluidic Gas Sensors: Detection Principle and Applications
title Microfluidic Gas Sensors: Detection Principle and Applications
title_full Microfluidic Gas Sensors: Detection Principle and Applications
title_fullStr Microfluidic Gas Sensors: Detection Principle and Applications
title_full_unstemmed Microfluidic Gas Sensors: Detection Principle and Applications
title_short Microfluidic Gas Sensors: Detection Principle and Applications
title_sort microfluidic gas sensors: detection principle and applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607434/
https://www.ncbi.nlm.nih.gov/pubmed/36296069
http://dx.doi.org/10.3390/mi13101716
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