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Microfluidic Gas Sensors: Detection Principle and Applications
With the rapid growth of emerging point-of-use (POU)/point-of-care (POC) detection technologies, miniaturized sensors for the real-time detection of gases and airborne pathogens have become essential to fight pollution, emerging contaminants, and pandemics. However, the low-cost development of minia...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607434/ https://www.ncbi.nlm.nih.gov/pubmed/36296069 http://dx.doi.org/10.3390/mi13101716 |
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author | Kaaliveetil, Sreerag Yang, Juliana Alssaidy, Saud Li, Zhenglong Cheng, Yu-Hsuan Menon, Niranjan Haridas Chande, Charmi Basuray, Sagnik |
author_facet | Kaaliveetil, Sreerag Yang, Juliana Alssaidy, Saud Li, Zhenglong Cheng, Yu-Hsuan Menon, Niranjan Haridas Chande, Charmi Basuray, Sagnik |
author_sort | Kaaliveetil, Sreerag |
collection | PubMed |
description | With the rapid growth of emerging point-of-use (POU)/point-of-care (POC) detection technologies, miniaturized sensors for the real-time detection of gases and airborne pathogens have become essential to fight pollution, emerging contaminants, and pandemics. However, the low-cost development of miniaturized gas sensors without compromising selectivity, sensitivity, and response time remains challenging. Microfluidics is a promising technology that has been exploited for decades to overcome such limitations, making it an excellent candidate for POU/POC. However, microfluidic-based gas sensors remain a nascent field. In this review, the evolution of microfluidic gas sensors from basic electronic techniques to more advanced optical techniques such as surface-enhanced Raman spectroscopy to detect analytes is documented in detail. This paper focuses on the various detection methodologies used in microfluidic-based devices for detecting gases and airborne pathogens. Non-continuous microfluidic devices such as bubble/droplet-based microfluidics technology that have been employed to detect gases and airborne pathogens are also discussed. The selectivity, sensitivity, advantages/disadvantages vis-a-vis response time, and fabrication costs for all the microfluidic sensors are tabulated. The microfluidic sensors are grouped based on the target moiety, such as air pollutants such as carbon monoxide and nitrogen oxides, and airborne pathogens such as E. coli and SARS-CoV-2. The possible application scenarios for the various microfluidic devices are critically examined. |
format | Online Article Text |
id | pubmed-9607434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96074342022-10-28 Microfluidic Gas Sensors: Detection Principle and Applications Kaaliveetil, Sreerag Yang, Juliana Alssaidy, Saud Li, Zhenglong Cheng, Yu-Hsuan Menon, Niranjan Haridas Chande, Charmi Basuray, Sagnik Micromachines (Basel) Review With the rapid growth of emerging point-of-use (POU)/point-of-care (POC) detection technologies, miniaturized sensors for the real-time detection of gases and airborne pathogens have become essential to fight pollution, emerging contaminants, and pandemics. However, the low-cost development of miniaturized gas sensors without compromising selectivity, sensitivity, and response time remains challenging. Microfluidics is a promising technology that has been exploited for decades to overcome such limitations, making it an excellent candidate for POU/POC. However, microfluidic-based gas sensors remain a nascent field. In this review, the evolution of microfluidic gas sensors from basic electronic techniques to more advanced optical techniques such as surface-enhanced Raman spectroscopy to detect analytes is documented in detail. This paper focuses on the various detection methodologies used in microfluidic-based devices for detecting gases and airborne pathogens. Non-continuous microfluidic devices such as bubble/droplet-based microfluidics technology that have been employed to detect gases and airborne pathogens are also discussed. The selectivity, sensitivity, advantages/disadvantages vis-a-vis response time, and fabrication costs for all the microfluidic sensors are tabulated. The microfluidic sensors are grouped based on the target moiety, such as air pollutants such as carbon monoxide and nitrogen oxides, and airborne pathogens such as E. coli and SARS-CoV-2. The possible application scenarios for the various microfluidic devices are critically examined. MDPI 2022-10-11 /pmc/articles/PMC9607434/ /pubmed/36296069 http://dx.doi.org/10.3390/mi13101716 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kaaliveetil, Sreerag Yang, Juliana Alssaidy, Saud Li, Zhenglong Cheng, Yu-Hsuan Menon, Niranjan Haridas Chande, Charmi Basuray, Sagnik Microfluidic Gas Sensors: Detection Principle and Applications |
title | Microfluidic Gas Sensors: Detection Principle and Applications |
title_full | Microfluidic Gas Sensors: Detection Principle and Applications |
title_fullStr | Microfluidic Gas Sensors: Detection Principle and Applications |
title_full_unstemmed | Microfluidic Gas Sensors: Detection Principle and Applications |
title_short | Microfluidic Gas Sensors: Detection Principle and Applications |
title_sort | microfluidic gas sensors: detection principle and applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607434/ https://www.ncbi.nlm.nih.gov/pubmed/36296069 http://dx.doi.org/10.3390/mi13101716 |
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