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Metformin Treatment Modulates Long Non-Coding RNA Isoforms Expression in Human Cells

Long noncoding RNAs (lncRNAs) undergo splicing and have multiple transcribed isoforms. Nevertheless, for lncRNAs, as well as for mRNA, measurements of expression are routinely performed only at the gene level. Metformin is the first-line oral therapy for type 2 diabetes mellitus and other metabolic...

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Detalles Bibliográficos
Autores principales: da Conceição, Izabela Mamede C. A., Luscher-Dias, Thomaz, Queiroz, Lúcio R., de Melo, Ana Gabrielle B., Machado, Carlos Renato, Gomes, Karina B., Souza, Renan P., Luizon, Marcelo R., Franco, Glória R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607547/
https://www.ncbi.nlm.nih.gov/pubmed/36287120
http://dx.doi.org/10.3390/ncrna8050068