Glycoconjugation of Quinoline Derivatives Using the C-6 Position in Sugars as a Strategy for Improving the Selectivity and Cytotoxicity of Functionalized Compounds

Based on the Warburg effect and the increased demand for glucose by tumor cells, a targeted drug delivery strategy was developed. A series of new glycoconjugates with increased ability to interact with GLUT transporters, responsible for the transport of sugars to cancer cells, were synthesized. Glyc...

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Detalles Bibliográficos
Autores principales: Domińska, Monika, Pastuch-Gawołek, Gabriela, Skonieczna, Magdalena, Szeja, Wiesław, Domiński, Adrian, Kurcok, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607644/
https://www.ncbi.nlm.nih.gov/pubmed/36296513
http://dx.doi.org/10.3390/molecules27206918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607644/
https://www.ncbi.nlm.nih.gov/pubmed/36296513
http://dx.doi.org/10.3390/molecules27206918

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