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Explainable AI for clinical and remote health applications: a survey on tabular and time series data

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques are defined to unveil the reasoning behind the system’s predi...

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Autores principales: Di Martino, Flavio, Delmastro, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607788/
https://www.ncbi.nlm.nih.gov/pubmed/36320613
http://dx.doi.org/10.1007/s10462-022-10304-3
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author Di Martino, Flavio
Delmastro, Franca
author_facet Di Martino, Flavio
Delmastro, Franca
author_sort Di Martino, Flavio
collection PubMed
description Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques are defined to unveil the reasoning behind the system’s predictions and decisions, and they become even more critical when dealing with sensitive and personal health data. It is worth noting that XAI has not gathered the same attention across different research areas and data types, especially in healthcare. In particular, many clinical and remote health applications are based on tabular and time series data, respectively, and XAI is not commonly analysed on these data types, while computer vision and Natural Language Processing (NLP) are the reference applications. To provide an overview of XAI methods that are most suitable for tabular and time series data in the healthcare domain, this paper provides a review of the literature in the last 5 years, illustrating the type of generated explanations and the efforts provided to evaluate their relevance and quality. Specifically, we identify clinical validation, consistency assessment, objective and standardised quality evaluation, and human-centered quality assessment as key features to ensure effective explanations for the end users. Finally, we highlight the main research challenges in the field as well as the limitations of existing XAI methods.
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spelling pubmed-96077882022-10-28 Explainable AI for clinical and remote health applications: a survey on tabular and time series data Di Martino, Flavio Delmastro, Franca Artif Intell Rev Article Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques are defined to unveil the reasoning behind the system’s predictions and decisions, and they become even more critical when dealing with sensitive and personal health data. It is worth noting that XAI has not gathered the same attention across different research areas and data types, especially in healthcare. In particular, many clinical and remote health applications are based on tabular and time series data, respectively, and XAI is not commonly analysed on these data types, while computer vision and Natural Language Processing (NLP) are the reference applications. To provide an overview of XAI methods that are most suitable for tabular and time series data in the healthcare domain, this paper provides a review of the literature in the last 5 years, illustrating the type of generated explanations and the efforts provided to evaluate their relevance and quality. Specifically, we identify clinical validation, consistency assessment, objective and standardised quality evaluation, and human-centered quality assessment as key features to ensure effective explanations for the end users. Finally, we highlight the main research challenges in the field as well as the limitations of existing XAI methods. Springer Netherlands 2022-10-26 2023 /pmc/articles/PMC9607788/ /pubmed/36320613 http://dx.doi.org/10.1007/s10462-022-10304-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Di Martino, Flavio
Delmastro, Franca
Explainable AI for clinical and remote health applications: a survey on tabular and time series data
title Explainable AI for clinical and remote health applications: a survey on tabular and time series data
title_full Explainable AI for clinical and remote health applications: a survey on tabular and time series data
title_fullStr Explainable AI for clinical and remote health applications: a survey on tabular and time series data
title_full_unstemmed Explainable AI for clinical and remote health applications: a survey on tabular and time series data
title_short Explainable AI for clinical and remote health applications: a survey on tabular and time series data
title_sort explainable ai for clinical and remote health applications: a survey on tabular and time series data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607788/
https://www.ncbi.nlm.nih.gov/pubmed/36320613
http://dx.doi.org/10.1007/s10462-022-10304-3
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