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High-Throughput, Quantitative Analysis of Peptide-Exchanged MHCI Complexes by Native Mass Spectrometry

[Image: see text] Immune monitoring in cancer immunotherapy involves screening CD8+ T-cell responses against neoantigens, the tumor-specific peptides presented by Major histocompatibility complex Class I (MHCI) on the cell surface. High-throughput immune monitoring requires methods to produce and ch...

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Detalles Bibliográficos
Autores principales:	Schachner, Luis F., Phung, Wilson, Han, Guanghui, Darwish, Martine, Bell, Ashley, Mellors, J. Scott, Srzentic, Kristina, Huguet, Romain, Blanchette, Craig, Sandoval, Wendy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607865/ https://www.ncbi.nlm.nih.gov/pubmed/36179215 http://dx.doi.org/10.1021/acs.analchem.2c02423

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