Neuropsychological decrements in midlife type-2 diabetes are not associated with peripheral NLRP3 inflammasome responsiveness

Midlife Type 2 Diabetes Mellitus (T2DM) is associated with an increased risk of Alzheimer Disease (AD) in later life, with altered inflammatory responses postulated as key pathological drivers. Previous studies have demonstrated increased responsiveness to NLR family pyrin domain containing 3 (NLRP3...

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Detalles Bibliográficos
Autores principales: Dyer, Adam H., Batten, Isabella, Reddy, Conor, Townsend, Liam, Woods, Conor P., O’Neill, Desmond, Gibney, James, Kennelly, Sean P., Bourke, Nollaig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607906/
https://www.ncbi.nlm.nih.gov/pubmed/36311713
http://dx.doi.org/10.3389/fimmu.2022.1021351

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