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Clinical Application of Thromboelastography in Acute Ischemic Stroke

Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay in waiting for the results of conventional coagula...

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Detalles Bibliográficos
Autores principales: Chen, Feng, Zhang, Liren, Bai, Xiaolin, Wang, Xiuzhe, Geng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608017/
https://www.ncbi.nlm.nih.gov/pubmed/36285384
http://dx.doi.org/10.1177/10760296221131801
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author Chen, Feng
Zhang, Liren
Bai, Xiaolin
Wang, Xiuzhe
Geng, Zhi
author_facet Chen, Feng
Zhang, Liren
Bai, Xiaolin
Wang, Xiuzhe
Geng, Zhi
author_sort Chen, Feng
collection PubMed
description Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay in waiting for the results of conventional coagulation tests in candidate patients for intravenous thrombolysis therapy. Heterogeneous responses to antiplatelet, intravascular thrombolysis, and endovascular therapies also worsen the situation. Thromboelastography (TEG), as a global and portable detection method for hemostasis, facilitates clinicians in disease monitoring, treatment evaluation, and prognosis prediction in AIS. In this narrative review, we provided a comprehensive summary of the clinical application of TEG in ischemic stroke and gave insights to further studies.
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spelling pubmed-96080172022-10-28 Clinical Application of Thromboelastography in Acute Ischemic Stroke Chen, Feng Zhang, Liren Bai, Xiaolin Wang, Xiuzhe Geng, Zhi Clin Appl Thromb Hemost Review Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay in waiting for the results of conventional coagulation tests in candidate patients for intravenous thrombolysis therapy. Heterogeneous responses to antiplatelet, intravascular thrombolysis, and endovascular therapies also worsen the situation. Thromboelastography (TEG), as a global and portable detection method for hemostasis, facilitates clinicians in disease monitoring, treatment evaluation, and prognosis prediction in AIS. In this narrative review, we provided a comprehensive summary of the clinical application of TEG in ischemic stroke and gave insights to further studies. SAGE Publications 2022-10-25 /pmc/articles/PMC9608017/ /pubmed/36285384 http://dx.doi.org/10.1177/10760296221131801 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Chen, Feng
Zhang, Liren
Bai, Xiaolin
Wang, Xiuzhe
Geng, Zhi
Clinical Application of Thromboelastography in Acute Ischemic Stroke
title Clinical Application of Thromboelastography in Acute Ischemic Stroke
title_full Clinical Application of Thromboelastography in Acute Ischemic Stroke
title_fullStr Clinical Application of Thromboelastography in Acute Ischemic Stroke
title_full_unstemmed Clinical Application of Thromboelastography in Acute Ischemic Stroke
title_short Clinical Application of Thromboelastography in Acute Ischemic Stroke
title_sort clinical application of thromboelastography in acute ischemic stroke
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608017/
https://www.ncbi.nlm.nih.gov/pubmed/36285384
http://dx.doi.org/10.1177/10760296221131801
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