Hot-Melt Extrusion of the Thermo-Sensitive Peptidomimetic Drug Enalapril Maleate

The aim of this research was the production of extrudates for the treatment of hypertension and heart failure and the investigation of the degradation of the peptidomimetic drug enalapril maleate (EM) during hot-melt extrusion (HME). A fast HPLC method was developed to quantify enalapril maleate and...

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Detalles Bibliográficos
Autores principales: Hoffmann, Lena, Breitkreutz, Jörg, Quodbach, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608079/
https://www.ncbi.nlm.nih.gov/pubmed/36297525
http://dx.doi.org/10.3390/pharmaceutics14102091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608079/
https://www.ncbi.nlm.nih.gov/pubmed/36297525
http://dx.doi.org/10.3390/pharmaceutics14102091

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