NetrinG1(+) Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

It is projected that in 5 years, pancreatic cancer will become the second deadliest cancer in the United States. A unique aspect of pancreatic ductal adenocarcinoma (PDAC) is its stroma; rich in cancer-associated fibroblasts (CAFs) and a dense CAF-generated extracellular matrix (ECM). These pathogen...

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Detalles Bibliográficos
Autores principales: Raghavan, Kristopher S., Francescone, Ralph, Franco-Barraza, Janusz, Gardiner, Jaye C., Vendramini-Costa, Débora B., Luong, Tiffany, Pourmandi, Narges, Andren, Anthony, Kurimchak, Alison, Ogier, Charline, Campbell, Paul M., Duncan, James S., Lyssiotis, Costas A., Languino, Lucia R., Cukierman, Edna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608356/
https://www.ncbi.nlm.nih.gov/pubmed/36310768
http://dx.doi.org/10.1158/2767-9764.CRC-21-0147

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