Modification at the C2′-O-Position with 2-Methylbenzothiophene Induces Unique Structural Changes and Thermal Transitions on Duplexes of RNA and DNA

[Image: see text] Oligonucleotides can be chemically modified for a variety of applications that include their use as biomaterials, in therapeutics, or as tools to understand biochemical processes, among others. This work focuses on the functionalization of oligonucleotides of RNA and DNA (12- or 14...

Descripción completa

Detalles Bibliográficos
Autores principales: Phillips, Cheyenne N., Choi, Madeline, Huynh, Kim Ngan, Wang, Haobin, Resendiz, Marino J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608412/
https://www.ncbi.nlm.nih.gov/pubmed/36312363
http://dx.doi.org/10.1021/acsomega.2c04784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608412/
https://www.ncbi.nlm.nih.gov/pubmed/36312363
http://dx.doi.org/10.1021/acsomega.2c04784

Ejemplares similares