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Distinct CD4+ T cell signature in ANA-positive young adult patients

Failure of immune tolerance can lead to autoantibody production resulting in autoimmune diseases, a broad spectrum of organ-specific or systemic disorders. Immune tolerance mechanisms regulate autoreactive T and B cells, yet some lymphocytes escape and promote autoantibody production. CD4+ T cell dy...

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Detalles Bibliográficos
Autores principales: Dei Zotti, Flavia, Moriconi, Chiara, Qiu, Annie, Miller, Anabel, Hudson, Krystalyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608560/
https://www.ncbi.nlm.nih.gov/pubmed/36311777
http://dx.doi.org/10.3389/fimmu.2022.972127

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