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Delta-8 Tetrahydrocannabinol Product Impurities

Due to increased concerns regarding unidentified impurities in delta-8 tetrahydrocannabinol (Δ-8 THC) consumer products, a study using Nuclear Magnetic Resonance (NMR), high performance liquid chromatography (HPLC), and mass spectrometry (MS) was conducted to further investigate these products. Ten...

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Autores principales: Ray, Colleen L., Bylo, Madison P., Pescaglia, Jonny, Gawenis, James A., Greenlief, C. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608670/
https://www.ncbi.nlm.nih.gov/pubmed/36296514
http://dx.doi.org/10.3390/molecules27206924
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author Ray, Colleen L.
Bylo, Madison P.
Pescaglia, Jonny
Gawenis, James A.
Greenlief, C. Michael
author_facet Ray, Colleen L.
Bylo, Madison P.
Pescaglia, Jonny
Gawenis, James A.
Greenlief, C. Michael
author_sort Ray, Colleen L.
collection PubMed
description Due to increased concerns regarding unidentified impurities in delta-8 tetrahydrocannabinol (Δ-8 THC) consumer products, a study using Nuclear Magnetic Resonance (NMR), high performance liquid chromatography (HPLC), and mass spectrometry (MS) was conducted to further investigate these products. Ten Δ-8 THC products, including distillates and ready to use vaporizer cartridges, were analyzed. The results yield findings that the tested products contain several impurities in concentrations far beyond what is declared on certificates of analysis for these products. As Δ-8 THC is a synthetic product synthesized from cannabidiol (CBD), there are valid concerns regarding the presence of impurities in these products with unknown effects on the human body. Compounding this problem is apparent inadequate testing of these products by producers and independent laboratories.
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spelling pubmed-96086702022-10-28 Delta-8 Tetrahydrocannabinol Product Impurities Ray, Colleen L. Bylo, Madison P. Pescaglia, Jonny Gawenis, James A. Greenlief, C. Michael Molecules Article Due to increased concerns regarding unidentified impurities in delta-8 tetrahydrocannabinol (Δ-8 THC) consumer products, a study using Nuclear Magnetic Resonance (NMR), high performance liquid chromatography (HPLC), and mass spectrometry (MS) was conducted to further investigate these products. Ten Δ-8 THC products, including distillates and ready to use vaporizer cartridges, were analyzed. The results yield findings that the tested products contain several impurities in concentrations far beyond what is declared on certificates of analysis for these products. As Δ-8 THC is a synthetic product synthesized from cannabidiol (CBD), there are valid concerns regarding the presence of impurities in these products with unknown effects on the human body. Compounding this problem is apparent inadequate testing of these products by producers and independent laboratories. MDPI 2022-10-15 /pmc/articles/PMC9608670/ /pubmed/36296514 http://dx.doi.org/10.3390/molecules27206924 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ray, Colleen L.
Bylo, Madison P.
Pescaglia, Jonny
Gawenis, James A.
Greenlief, C. Michael
Delta-8 Tetrahydrocannabinol Product Impurities
title Delta-8 Tetrahydrocannabinol Product Impurities
title_full Delta-8 Tetrahydrocannabinol Product Impurities
title_fullStr Delta-8 Tetrahydrocannabinol Product Impurities
title_full_unstemmed Delta-8 Tetrahydrocannabinol Product Impurities
title_short Delta-8 Tetrahydrocannabinol Product Impurities
title_sort delta-8 tetrahydrocannabinol product impurities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608670/
https://www.ncbi.nlm.nih.gov/pubmed/36296514
http://dx.doi.org/10.3390/molecules27206924
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