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Development of a Luliconazole Nanoemulsion as a Prospective Ophthalmic Delivery System for the Treatment of Fungal Keratitis: In Vitro and In Vivo Evaluation
Luliconazole (LCZ), a novel imidazole drug, has broad-spectrum and potential antifungal effects, which makes it a possible cure for fungal keratitis; nevertheless, its medical use in ocular infections is hindered by its poor solubility. The purpose of this study was to design and optimize LCZ nanoem...
Autores principales: | Yang, Jingjing, Liang, Zhen, Lu, Ping, Song, Fei, Zhang, Zhen, Zhou, Tianyang, Li, Jingguo, Zhang, Junjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608689/ https://www.ncbi.nlm.nih.gov/pubmed/36297487 http://dx.doi.org/10.3390/pharmaceutics14102052 |
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