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Case report: Success of tepotinib therapy in overcoming resistance to osimertinib in a patient with EGFR-mutant lung adenocarcinoma with a potential acquired MET exon 14 skipping mutation
Osimertinib is a standard therapy for the treatment of advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor gene (EGFR) mutations, but most patients with EGFR-mutant NSCLC develop secondary resistance to osimertinib. Mesenchymal-epithelial transition gene (MET) alte...
Autores principales: | Takamori, Shinkichi, Seto, Takashi, Yamaguchi, Masafumi, Kinoshita, Fumihiko, Fujishita, Takatoshi, Ito, Kensaku, Toyozawa, Ryo, Shoji, Fumihiro, Okamoto, Tatsuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608750/ https://www.ncbi.nlm.nih.gov/pubmed/36313664 http://dx.doi.org/10.3389/fonc.2022.965741 |
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