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Surface layer protein A from hypervirulent Clostridioides difficile ribotypes induce significant changes in the gene expression of tight junctions and inflammatory response in human intestinal epithelial cells

BACKGROUND: Surface layer protein A (SlpA), the primary outermost structure of Clostridioides difficile, plays an essential role in C. difficile pathogenesis, although its interaction with host intestinal cells are yet to be understood. The aim of this study was to investigate the effects of SlpA ex...

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Detalles Bibliográficos
Autores principales:	Noori, Maryam, Azimirad, Masoumeh, Eslami, Gita, Looha, Mehdi Azizmohammad, Yadegar, Abbas, Ghalavand, Zohreh, Zali, Mohammad Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608920/ https://www.ncbi.nlm.nih.gov/pubmed/36303110 http://dx.doi.org/10.1186/s12866-022-02665-0

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