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In Vitro and In Vivo Relevant Antineoplastic Activity of Platinum(II) Complexes toward Triple-Negative MDA-MB-231 Breast Cancer Cell Line

Two platinum complexes [Pt(HL3)Cl]·H(2)O (3) and [Pt(HL4)Cl]·H(2)O (4) containing α- and β-naphthyl groups, respectively, were investigated in more detail in vitro and in vivo for antineoplastic activity. The cytotoxicity activity induced by these platinum(II) compounds against breast cancer (MDA-MB...

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Detalles Bibliográficos
Autores principales: Maciel, Leide Laura Figueiredo, Silva, Marina Barreto, Moreira, Rafaela Oliveira, Cardoso, Ana Paula, Fernandes, Christiane, Horn, Adolfo, de Aquino Almeida, João Carlos, Kanashiro, Milton Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609024/
https://www.ncbi.nlm.nih.gov/pubmed/36297448
http://dx.doi.org/10.3390/pharmaceutics14102013