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Preparation of Chiral Enantioenriched Densely Substituted Cyclopropyl Azoles, Amines, and Ethers via Formal S(N)2′ Substitution of Bromocylopropanes

Enantiomerically enriched cyclopropyl ethers, amines, and cyclopropylazole derivatives possessing three stereogenic carbon atoms in a small cycle are obtained via the diastereoselective, formal nucleophilic substitution of chiral, non-racemic bromocyclopropanes. The key feature of this methodology i...

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Detalles Bibliográficos
Autores principales: Straub, Hillary, Ryabchuk, Pavel, Rubina, Marina, Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609026/
https://www.ncbi.nlm.nih.gov/pubmed/36296663
http://dx.doi.org/10.3390/molecules27207069