Aptamer-Functionalized Nanoparticles Mediate PD-L1 siRNA Delivery for Effective Gene Silencing in Triple-Negative Breast Cancer Cells

Small interfering RNA (siRNA) therapies require effective delivery vehicles capable of carrying the siRNA cargo into target cells. To achieve tumor-targeting, a drug delivery system would have to incorporate ligands that specifically bind to receptors expressed on cancer cells to function as portals...

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Detalles Bibliográficos
Autores principales: Camorani, Simona, Tortorella, Silvia, Agnello, Lisa, Spanu, Chiara, d’Argenio, Annachiara, Nilo, Roberto, Zannetti, Antonella, Locatelli, Erica, Fedele, Monica, Comes Franchini, Mauro, Cerchia, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609037/
https://www.ncbi.nlm.nih.gov/pubmed/36297659
http://dx.doi.org/10.3390/pharmaceutics14102225

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