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Diastereoselective Synthesis of Highly Functionalized Proline Derivatives

An efficient way to access highly functionalized proline derivatives was developed based on a Cu(I)-catalyzed reaction between CF(3)-substituted allenynes and tosylazide, which involved a cascade of [3 + 2]-cycloaddition/ketenimine and a rearrangement/Alder-ene cyclization to afford the new proline...

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Detalles Bibliográficos
Autores principales:	Philippova, Anna N., Vorobyeva, Daria V., Gribanov, Pavel S., Dolgushin, Fedor M., Osipov, Sergey N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609175/ https://www.ncbi.nlm.nih.gov/pubmed/36296490 http://dx.doi.org/10.3390/molecules27206898

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