Engineering of global transcription factor FruR to redirect the carbon flow in Escherichia coli for enhancing l-phenylalanine biosynthesis

BACKGROUND: The catabolite repressor/activator protein (FruR) is a global regulatory protein known to control the expression of several genes concerned with carbon utilization and energy metabolism. This study aimed to illustrate effects of the FruR mutant on the (L-)phenylalanine ((L-)PHE) producin...

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Detalles Bibliográficos
Autores principales: Chen, Minliang, Liang, Hengyu, Han, Chao, Zhou, Peng, Xing, Zhiwei, Chen, Qianqian, Liu, Yongyu, Xie, Gou-an, Xie, Rufei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609185/
https://www.ncbi.nlm.nih.gov/pubmed/36289548
http://dx.doi.org/10.1186/s12934-022-01954-7

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