Pembrolizumab combined with low-dose cyclophosphamide and intra-tumoral injection of the toll-like receptor 4 agonist G100 in patients with advanced pretreated soft tissue sarcoma: results from the PEMBROSARC basket study

Soft tissue sarcomas (STS) are heterogeneous mesenchymal tumors with limited therapeutic options in the advanced setting. Immune checkpoint inhibitors have been shown to have significant clinical activity in inflamed STS which are characterized by the presence of tertiary lymphoid structures (TLS)....

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Detalles Bibliográficos
Autores principales: Spalato-Ceruso, Mariella, Bouteiller, Fanny, Guegan, Jean-Philippe, Toulmonde, Maud, Bessede, Alban, Kind, Michèle, Cousin, Sophie, Buy, Xavier, Palussiere, Jean, Le Loarer, François, Dadone-Montaudie, Berengere, Pulido, Marina, Italiano, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609223/
https://www.ncbi.nlm.nih.gov/pubmed/36303228
http://dx.doi.org/10.1186/s13045-022-01377-2

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