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LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

BACKGROUND: Tumor-initiating cells (TIC), also known as cancer stem cells, are considered a specific subpopulation of cells necessary for cancer initiation and metastasis; however, the mechanisms by which they acquire metastatic traits are not well understood. METHODS: LAMC2 transcriptional levels w...

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Detalles Bibliográficos
Autores principales: Cave, Donatella Delle, Buonaiuto, Silvia, Sainz, Bruno, Fantuz, Marco, Mangini, Maria, Carrer, Alessandro, Di Domenico, Annalisa, Iavazzo, Tea Teresa, Andolfi, Gennaro, Cortina, Carme, Sevillano, Marta, Heeschen, Christopher, Colonna, Vincenza, Corona, Marco, Cucciardi, Antonio, Di Guida, Martina, Batlle, Eduard, De Luca, Annachiara, Lonardo, Enza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609288/
https://www.ncbi.nlm.nih.gov/pubmed/36289544
http://dx.doi.org/10.1186/s13046-022-02516-w