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Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department
Pesticide poisoning in pediatric patients is still an important reason for presenting to the emergency department in Romania. In this context, the present study aims to raise awareness of the toxicological impact of pesticides on human health in pediatrics. For this purpose, the demographic characte...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609388/ https://www.ncbi.nlm.nih.gov/pubmed/36287862 http://dx.doi.org/10.3390/toxics10100582 |
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author | Caba, Ioana-Cezara Ștreangă, Violeta Dobrin, Mona-Elisabeta Jităreanu, Cristina Jităreanu, Alexandra Profire, Bianca-Ștefania Apotrosoaei, Maria Focșa, Alin-Viorel Caba, Bogdan Agoroaei, Luminița |
author_facet | Caba, Ioana-Cezara Ștreangă, Violeta Dobrin, Mona-Elisabeta Jităreanu, Cristina Jităreanu, Alexandra Profire, Bianca-Ștefania Apotrosoaei, Maria Focșa, Alin-Viorel Caba, Bogdan Agoroaei, Luminița |
author_sort | Caba, Ioana-Cezara |
collection | PubMed |
description | Pesticide poisoning in pediatric patients is still an important reason for presenting to the emergency department in Romania. In this context, the present study aims to raise awareness of the toxicological impact of pesticides on human health in pediatrics. For this purpose, the demographic characteristics, clinical assessment, and outcome of pediatric patients with acute pesticide poisoning admitted to the toxicology department of “Saint Mary” Emergency Children’s Hospital from Iasi, were analyzed. This retrospective study focused on the clinical and laboratory data of patients aged under 18 years diagnosed with acute pesticide poisoning between 2010–2020. The statistical analysis was performed using the Statistica 10 package. A total of 49 patients presented with manifestations of acute pesticide poisoning, and the most common pesticide involved was diazinon. The most frequent exposure route was accidentally ingesting pesticide products (95%). The primary clinical manifestations were toxic encephalopathy, coma, depressive disorder, gastric disorders, and respiratory failure. Changes in the glycemic status, liver, and kidney damage were also present. Treatment included decontamination, administration of antidote, supportive care, and recommendations to be closely monitored to avoid a new incident. These results highlight the toxic potential of pesticides on human health and their biological consequences, which require an increase in consciousness of the precautions imposed on their use, especially when children are nearby. |
format | Online Article Text |
id | pubmed-9609388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96093882022-10-28 Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department Caba, Ioana-Cezara Ștreangă, Violeta Dobrin, Mona-Elisabeta Jităreanu, Cristina Jităreanu, Alexandra Profire, Bianca-Ștefania Apotrosoaei, Maria Focșa, Alin-Viorel Caba, Bogdan Agoroaei, Luminița Toxics Article Pesticide poisoning in pediatric patients is still an important reason for presenting to the emergency department in Romania. In this context, the present study aims to raise awareness of the toxicological impact of pesticides on human health in pediatrics. For this purpose, the demographic characteristics, clinical assessment, and outcome of pediatric patients with acute pesticide poisoning admitted to the toxicology department of “Saint Mary” Emergency Children’s Hospital from Iasi, were analyzed. This retrospective study focused on the clinical and laboratory data of patients aged under 18 years diagnosed with acute pesticide poisoning between 2010–2020. The statistical analysis was performed using the Statistica 10 package. A total of 49 patients presented with manifestations of acute pesticide poisoning, and the most common pesticide involved was diazinon. The most frequent exposure route was accidentally ingesting pesticide products (95%). The primary clinical manifestations were toxic encephalopathy, coma, depressive disorder, gastric disorders, and respiratory failure. Changes in the glycemic status, liver, and kidney damage were also present. Treatment included decontamination, administration of antidote, supportive care, and recommendations to be closely monitored to avoid a new incident. These results highlight the toxic potential of pesticides on human health and their biological consequences, which require an increase in consciousness of the precautions imposed on their use, especially when children are nearby. MDPI 2022-10-02 /pmc/articles/PMC9609388/ /pubmed/36287862 http://dx.doi.org/10.3390/toxics10100582 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Caba, Ioana-Cezara Ștreangă, Violeta Dobrin, Mona-Elisabeta Jităreanu, Cristina Jităreanu, Alexandra Profire, Bianca-Ștefania Apotrosoaei, Maria Focșa, Alin-Viorel Caba, Bogdan Agoroaei, Luminița Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department |
title | Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department |
title_full | Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department |
title_fullStr | Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department |
title_full_unstemmed | Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department |
title_short | Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department |
title_sort | clinical assessment of acute organophosphorus pesticide poisoning in pediatric patients admitted to the toxicology emergency department |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609388/ https://www.ncbi.nlm.nih.gov/pubmed/36287862 http://dx.doi.org/10.3390/toxics10100582 |
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