Prostate Cancer Biochemical Recurrence Resulted Negative on [(68)Ga]Ga-PSMA-11 but Positive on [(18)F]Fluoromethylcholine PET/CT

For prostate cancer (PCa) biochemical recurrence (BCR), the primarily suggested imaging technique by the European Association of Urology (EAU) guidelines is prostate-specific membrane antigen (PSMA) positron emission tomography/computer tomography (PET/CT). Indeed, the increased detection rate of PS...

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Detalles Bibliográficos
Autores principales: Laudicella, Riccardo, La Torre, Flavia, Davì, Valerio, Crocè, Ludovica, Aricò, Demetrio, Leonardi, Giuseppe, Russo, Simona, Minutoli, Fabio, Burger, Irene A., Baldari, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609559/
https://www.ncbi.nlm.nih.gov/pubmed/36287804
http://dx.doi.org/10.3390/tomography8050205
Descripción
Sumario:For prostate cancer (PCa) biochemical recurrence (BCR), the primarily suggested imaging technique by the European Association of Urology (EAU) guidelines is prostate-specific membrane antigen (PSMA) positron emission tomography/computer tomography (PET/CT). Indeed, the increased detection rate of PSMA PET/CT for early BCR has led to a fast and wide acceptance of this novel technology. However, PCa is a very heterogeneous disease, not always easily assessable with the highly specific PSMA PET with around 10% of cases occuring without PSMA expression. In this paper, we present the case of a patient with PCa BCR that resulted negative on [(68)Ga]Ga-PSMA-11 PET/CT, but positive on [(18)F]Fluoromethylcholine (Choline) PET/CT.

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