Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness

Asthma is characterized by chronic inflammation and a variable degree of airway hyperresponsiveness (AHR). Our previous papers documented a role for Nociceptin/Orphanin FQ (N/OFQ) and its receptor N/OFQ peptide (NOP) in AHR. Therefore, the aim of this study was to improve the bioavailability of N/OF...

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Detalles Bibliográficos
Autores principales: Mirra, Davida, Spaziano, Giuseppe, Esposito, Renata, Santonocito, Debora, Filosa, Rosanna, Roviezzo, Fiorentina, Malgieri, Gaetano, D’Abrosca, Gianluca, Iovino, Pasquale, Gallelli, Luca, Fattorusso, Roberto, Puglia, Carmelo, D’Agostino, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609590/
https://www.ncbi.nlm.nih.gov/pubmed/36297323
http://dx.doi.org/10.3390/ph15101210

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