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DExD/H Box Helicases DDX24 and DDX49 Inhibit Reactivation of Kaposi’s Sarcoma Associated Herpesvirus by Interacting with Viral mRNAs

Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus that is the causative agent of primary effusion lymphoma and Kaposi’s sarcoma. In healthy carriers, KSHV remains latent, but a compromised immune system can lead to lytic viral replication that increases the probability...

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Detalles Bibliográficos
Autores principales: Serfecz, Jacquelyn C., Hong, Yuan, Gay, Lauren A., Shekhar, Ritu, Turner, Peter C., Renne, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609691/
https://www.ncbi.nlm.nih.gov/pubmed/36298642
http://dx.doi.org/10.3390/v14102083