CC Genotype of GNAS c.393C>T (rs7121) Polymorphism Has a Protective Effect against Development of BK Viremia and BKV-Associated Nephropathy after Renal Transplant

The GNAS gene encodes the alpha-subunit of the stimulatory G-protein (Gαs) in humans and mice. The single-nucleotide polymorphism of GNAS, c.393C>T, is associated with an elevated production of Gαs and an increased formation of cyclic adenosine monophosphate (cAMP). In the present study, we analy...

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Detalles Bibliográficos
Autores principales: Peitz, Tobias, Möhlendick, Birte, Eisenberger, Ute, Siffert, Winfried, Heinemann, Falko Markus, Kribben, Andreas, Friebus-Kardash, Justa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609707/
https://www.ncbi.nlm.nih.gov/pubmed/36297195
http://dx.doi.org/10.3390/pathogens11101138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609707/
https://www.ncbi.nlm.nih.gov/pubmed/36297195
http://dx.doi.org/10.3390/pathogens11101138

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