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Guanfacine Normalizes the Overexpression of Presynaptic α-2A Adrenoceptor Signaling and Ameliorates Neuropathic Pain in a Chronic Animal Model of Type 1 Diabetes

Background: Diabetes is associated with several complications, including neuropathic pain, which is difficult to manage with currently available drugs. Descending noradrenergic neurons possess antinociceptive activity; however, their involvement in diabetic neuropathic pain remains to be explored. M...

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Detalles Bibliográficos
Autores principales:	Munawar, Neha, Nader, Joelle, Khadadah, Najat H., Al Madhoun, Ashraf, Al-Ali, Waleed, Varghese, Linu A., Masocha, Willias, Al-Mulla, Fahd, Bitar, Milad S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609777/ https://www.ncbi.nlm.nih.gov/pubmed/36297581 http://dx.doi.org/10.3390/pharmaceutics14102146

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