Cargando…
A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis
This study examined the effectiveness of a health care professional delivered low-carbohydrate diet program (Diversa Health Program) aiming to improve obesity/type-2-diabetes management for people living in Australia. 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017–August...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609895/ https://www.ncbi.nlm.nih.gov/pubmed/36297093 http://dx.doi.org/10.3390/nu14204406 |
_version_ | 1784819134043783168 |
---|---|
author | Brinkworth, Grant D. Wycherley, Thomas P. Taylor, Pennie J. Thompson, Campbell H. |
author_facet | Brinkworth, Grant D. Wycherley, Thomas P. Taylor, Pennie J. Thompson, Campbell H. |
author_sort | Brinkworth, Grant D. |
collection | PubMed |
description | This study examined the effectiveness of a health care professional delivered low-carbohydrate diet program (Diversa Health Program) aiming to improve obesity/type-2-diabetes management for people living in Australia. 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017–August 2021 for ≥30 days with pre-post data collected for ≥1 key outcome variable (body weight and HbA1c) were included in the analysis. Average participation duration was 218 ± 207 days with 5.4 ± 3.9 reported consultation visits. Body weight reduced from 92.3 ± 23.0 to 86.3 ± 21.1 kg (n = 506, p < 0.001). Weight loss was 0.9 ± 2.8 kg (1.3%), 4.5 ± 4.3 kg (5.7%) and 7.9 ± 7.2 kg (7.5%), respectively, for those with a classification of normal weight (n = 67), overweight (n = 122) and obese (n = 307) at commencement. HbA1c reduced from 6.0 ± 1.2 to 5.6 ± 0.7% (n = 212, p < 0.001). For members with a commencing HbA1c of <5.7% (n = 110), 5.7–6.4% (n = 55), and ≥6.5% (n = 48), HbA1c reduced −0.1 ± 0.2%, −0.3 ± 0.3%, and −1.4 ± 1.3%, respectively. For members with a commencing HbA1c ≥6.5%, 90% experienced a HbA1c reduction and 54% achieved a final HbA1c < 6.5%. With inclusion and exclusion of metformin, respectively, 124 and 82 diabetes medications were prescribed to 63 and 42 members that reduced to 82 and 35 medications prescribed to 51 and 26 members at final visit. A health care professional delivered low-carbohydrate diet program can facilitate weight loss and improve glycaemic control with greatest improvements and clinical relevance in individuals with worse baseline parameters. |
format | Online Article Text |
id | pubmed-9609895 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96098952022-10-28 A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis Brinkworth, Grant D. Wycherley, Thomas P. Taylor, Pennie J. Thompson, Campbell H. Nutrients Article This study examined the effectiveness of a health care professional delivered low-carbohydrate diet program (Diversa Health Program) aiming to improve obesity/type-2-diabetes management for people living in Australia. 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017–August 2021 for ≥30 days with pre-post data collected for ≥1 key outcome variable (body weight and HbA1c) were included in the analysis. Average participation duration was 218 ± 207 days with 5.4 ± 3.9 reported consultation visits. Body weight reduced from 92.3 ± 23.0 to 86.3 ± 21.1 kg (n = 506, p < 0.001). Weight loss was 0.9 ± 2.8 kg (1.3%), 4.5 ± 4.3 kg (5.7%) and 7.9 ± 7.2 kg (7.5%), respectively, for those with a classification of normal weight (n = 67), overweight (n = 122) and obese (n = 307) at commencement. HbA1c reduced from 6.0 ± 1.2 to 5.6 ± 0.7% (n = 212, p < 0.001). For members with a commencing HbA1c of <5.7% (n = 110), 5.7–6.4% (n = 55), and ≥6.5% (n = 48), HbA1c reduced −0.1 ± 0.2%, −0.3 ± 0.3%, and −1.4 ± 1.3%, respectively. For members with a commencing HbA1c ≥6.5%, 90% experienced a HbA1c reduction and 54% achieved a final HbA1c < 6.5%. With inclusion and exclusion of metformin, respectively, 124 and 82 diabetes medications were prescribed to 63 and 42 members that reduced to 82 and 35 medications prescribed to 51 and 26 members at final visit. A health care professional delivered low-carbohydrate diet program can facilitate weight loss and improve glycaemic control with greatest improvements and clinical relevance in individuals with worse baseline parameters. MDPI 2022-10-20 /pmc/articles/PMC9609895/ /pubmed/36297093 http://dx.doi.org/10.3390/nu14204406 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Brinkworth, Grant D. Wycherley, Thomas P. Taylor, Pennie J. Thompson, Campbell H. A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis |
title | A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis |
title_full | A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis |
title_fullStr | A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis |
title_full_unstemmed | A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis |
title_short | A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers—A Single-Arm Intervention Analysis |
title_sort | health care professional delivered low carbohydrate diet program reduces body weight, haemoglobin a1c, diabetes medication use and cardiovascular risk markers—a single-arm intervention analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609895/ https://www.ncbi.nlm.nih.gov/pubmed/36297093 http://dx.doi.org/10.3390/nu14204406 |
work_keys_str_mv | AT brinkworthgrantd ahealthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT wycherleythomasp ahealthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT taylorpenniej ahealthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT thompsoncampbellh ahealthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT brinkworthgrantd healthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT wycherleythomasp healthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT taylorpenniej healthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis AT thompsoncampbellh healthcareprofessionaldeliveredlowcarbohydratedietprogramreducesbodyweighthaemoglobina1cdiabetesmedicationuseandcardiovascularriskmarkersasinglearminterventionanalysis |