SAR Study and Molecular Mechanism Investigation of Novel Naphthoquinone-furan-2-cyanoacryloyl Hybrids with Antitumor Activity

A series of novel naphthoquinone-furan-2-cyanoacryloyl hybrids were designed; they were synthesized and preliminarily evaluated for their anti-proliferative activities in vitro against several cancer cell lines and normal cells. The most potent compound, 5c, inhibited the proliferation of HeLa cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Pingxian, Fan, Dongmei, Qiao, Wenliang, He, Xinlian, Zhang, Lidan, Jiang, Yunhan, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609996/
https://www.ncbi.nlm.nih.gov/pubmed/36297539
http://dx.doi.org/10.3390/pharmaceutics14102104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609996/
https://www.ncbi.nlm.nih.gov/pubmed/36297539
http://dx.doi.org/10.3390/pharmaceutics14102104

Ejemplares similares