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Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution

Sodium monofluorophosphate (MFP) is a component of fluoride-containing dentifrices and is more biosafe than the conventional sodium fluoride (NaF). MFP can respond not only on the tooth surface layer but also deep into the enamel. We aim to confirm that high concentrations of acid phosphate MFP (AP-...

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Autores principales: Satou, Ryouichi, Yamagishi, Atsushi, Takayanagi, Atsushi, Iwasaki, Miyu, Kamijo, Hideyuki, Sugihara, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610128/
https://www.ncbi.nlm.nih.gov/pubmed/36295363
http://dx.doi.org/10.3390/ma15207298
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author Satou, Ryouichi
Yamagishi, Atsushi
Takayanagi, Atsushi
Iwasaki, Miyu
Kamijo, Hideyuki
Sugihara, Naoki
author_facet Satou, Ryouichi
Yamagishi, Atsushi
Takayanagi, Atsushi
Iwasaki, Miyu
Kamijo, Hideyuki
Sugihara, Naoki
author_sort Satou, Ryouichi
collection PubMed
description Sodium monofluorophosphate (MFP) is a component of fluoride-containing dentifrices and is more biosafe than the conventional sodium fluoride (NaF). MFP can respond not only on the tooth surface layer but also deep into the enamel. We aim to confirm that high concentrations of acid phosphate MFP (AP-MFP, 9000 ppmF), used in professional care, could lead to a highly biosafe fluoride application method that acts through the deep enamel layers. Sample groups were respectively treated in vitro with NaF, acidulated phosphate fluoride (APF), MFP, and AP-MFP, and the samples were compared against an untreated group. Characterizations after fluoride application confirmed that MFP and AP-MFP treatments improved the acid resistance of enamel compared to that of conventional methods. Furthermore, the acid resistance of highly concentrated MFPs improved by using phosphoric acid. Although the acid resistance from the AP-MFP method is not as good as that using APF, AP-MFP can act both on the surface layer and deep into the enamel. Moreover, AP-MFP retains fluoride ions as much as APF does on the tooth surface. The proposed fluoride application method using AP-MFP introduces a dental treatment for acid resistance that is highly biosafe and penetrates deep layers of the enamel.
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spelling pubmed-96101282022-10-28 Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution Satou, Ryouichi Yamagishi, Atsushi Takayanagi, Atsushi Iwasaki, Miyu Kamijo, Hideyuki Sugihara, Naoki Materials (Basel) Article Sodium monofluorophosphate (MFP) is a component of fluoride-containing dentifrices and is more biosafe than the conventional sodium fluoride (NaF). MFP can respond not only on the tooth surface layer but also deep into the enamel. We aim to confirm that high concentrations of acid phosphate MFP (AP-MFP, 9000 ppmF), used in professional care, could lead to a highly biosafe fluoride application method that acts through the deep enamel layers. Sample groups were respectively treated in vitro with NaF, acidulated phosphate fluoride (APF), MFP, and AP-MFP, and the samples were compared against an untreated group. Characterizations after fluoride application confirmed that MFP and AP-MFP treatments improved the acid resistance of enamel compared to that of conventional methods. Furthermore, the acid resistance of highly concentrated MFPs improved by using phosphoric acid. Although the acid resistance from the AP-MFP method is not as good as that using APF, AP-MFP can act both on the surface layer and deep into the enamel. Moreover, AP-MFP retains fluoride ions as much as APF does on the tooth surface. The proposed fluoride application method using AP-MFP introduces a dental treatment for acid resistance that is highly biosafe and penetrates deep layers of the enamel. MDPI 2022-10-19 /pmc/articles/PMC9610128/ /pubmed/36295363 http://dx.doi.org/10.3390/ma15207298 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Satou, Ryouichi
Yamagishi, Atsushi
Takayanagi, Atsushi
Iwasaki, Miyu
Kamijo, Hideyuki
Sugihara, Naoki
Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution
title Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution
title_full Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution
title_fullStr Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution
title_full_unstemmed Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution
title_short Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution
title_sort improved enamel acid resistance by highly concentrated acidulated phosphate sodium monofluorophosphate solution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610128/
https://www.ncbi.nlm.nih.gov/pubmed/36295363
http://dx.doi.org/10.3390/ma15207298
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