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Possible Role of Bent Structure of Methylated Lithocholic Acid on Artificial and Plasma Membranes

Bile acids form micelles that are essential for the absorption of dietary lipids. However, excessive bile acid micelles can disrupt the plasma membrane by removing phospholipids, resulting in cell death. We hypothesized that the bent geometrical structure of the steroid scaffold of bile acids decrea...

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Detalles Bibliográficos
Autores principales: Iwasaki, Tomoyuki, Endo, Nobuyuki, Nakayama, Yuta, Kamei, Toshiyuki, Shimanouchi, Toshinori, Nakamura, Hidemi, Hayashi, Keita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610195/
https://www.ncbi.nlm.nih.gov/pubmed/36295756
http://dx.doi.org/10.3390/membranes12100997