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Possible Role of Bent Structure of Methylated Lithocholic Acid on Artificial and Plasma Membranes
Bile acids form micelles that are essential for the absorption of dietary lipids. However, excessive bile acid micelles can disrupt the plasma membrane by removing phospholipids, resulting in cell death. We hypothesized that the bent geometrical structure of the steroid scaffold of bile acids decrea...
Autores principales: | Iwasaki, Tomoyuki, Endo, Nobuyuki, Nakayama, Yuta, Kamei, Toshiyuki, Shimanouchi, Toshinori, Nakamura, Hidemi, Hayashi, Keita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610195/ https://www.ncbi.nlm.nih.gov/pubmed/36295756 http://dx.doi.org/10.3390/membranes12100997 |
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