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Lumpy Skin Disease Virus with Four Knocked Out Genes Was Attenuated In Vivo and Protects Cattle from Infection

Vaccination with live attenuated vaccines is a key element in the prevention of lumpy skin disease. The mechanism of virus attenuation by long-term passaging in sensitive systems remains unclear. Targeted inactivation of virulence genes is the most promising way to obtain attenuated viruses. Four vi...

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Detalles Bibliográficos
Autores principales:	Chervyakova, Olga, Issabek, Aisha, Sultankulova, Kulyaisan, Bopi, Arailym, Kozhabergenov, Nurlan, Omarova, Zamira, Tulendibayev, Ali, Aubakir, Nurdos, Orynbayev, Mukhit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610274/ https://www.ncbi.nlm.nih.gov/pubmed/36298570 http://dx.doi.org/10.3390/vaccines10101705

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