Immunogenicity and protective efficacy of a rhesus adenoviral vaccine targeting conserved COVID-19 replication transcription complex

The COVID-19 pandemic marks the third coronavirus pandemic this century (SARS-CoV-1, MERS, SARS-CoV-2), emphasizing the need to identify and evaluate conserved immunogens for a pan-sarbecovirus vaccine. Here we investigate the potential utility of a T-cell vaccine strategy targeting conserved region...

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Detalles Bibliográficos
Autores principales: Dagotto, Gabriel, Ventura, John D., Martinez, David R., Anioke, Tochi, Chung, Benjamin S., Siamatu, Mazuba, Barrett, Julia, Miller, Jessica, Schäfer, Alexandra, Yu, Jingyou, Tostanoski, Lisa H., Wagh, Kshitij, Baric, Ralph S., Korber, Bette, Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610341/
https://www.ncbi.nlm.nih.gov/pubmed/36302778
http://dx.doi.org/10.1038/s41541-022-00553-2

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