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SARS-CoV-2 Omicron variant is attenuated for replication in a polarized human lung epithelial cell model

SARS-CoV-2 and its emerging variants of concern remain a major threat for global health. Here we introduce an infection model based upon polarized human Alveolar Epithelial Lentivirus immortalized (hAELVi) cells grown at the air–liquid interface to estimate replication and epidemic potential of resp...

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Detalles Bibliográficos
Autores principales: Mache, Christin, Schulze, Jessica, Holland, Gudrun, Bourquain, Daniel, Gensch, Jean-Marc, Oh, Djin-Ye, Nitsche, Andreas, Dürrwald, Ralf, Laue, Michael, Wolff, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610361/
https://www.ncbi.nlm.nih.gov/pubmed/36302956
http://dx.doi.org/10.1038/s42003-022-04068-3

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