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SARS-CoV-2 Omicron variant is attenuated for replication in a polarized human lung epithelial cell model
SARS-CoV-2 and its emerging variants of concern remain a major threat for global health. Here we introduce an infection model based upon polarized human Alveolar Epithelial Lentivirus immortalized (hAELVi) cells grown at the air–liquid interface to estimate replication and epidemic potential of resp...
Autores principales: | Mache, Christin, Schulze, Jessica, Holland, Gudrun, Bourquain, Daniel, Gensch, Jean-Marc, Oh, Djin-Ye, Nitsche, Andreas, Dürrwald, Ralf, Laue, Michael, Wolff, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610361/ https://www.ncbi.nlm.nih.gov/pubmed/36302956 http://dx.doi.org/10.1038/s42003-022-04068-3 |
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