Cargando…
Nonhuman Primates Are Protected against Marburg Virus Disease by Vaccination with a Vesicular Stomatitis Virus Vector-Based Vaccine Prepared under Conditions to Allow Advancement to Human Clinical Trials
Vaccines are needed to disrupt or prevent continued outbreaks of filoviruses in humans across Western and Central Africa, including outbreaks of Marburg virus (MARV). As part of a filovirus vaccine product development plan, it is important to investigate dose response early in preclinical developmen...
Autores principales: | Cooper, Christopher L., Morrow, Gavin, Yuan, Maoli, Coleman, John W., Hou, Fuxiang, Reiserova, Lucia, Li, Shui L., Wagner, Denise, Carpov, Alexei, Wallace-Selman, Olivia, Valentin, Kristie, Choi, Yesle, Wilson, Aaron, Kilianski, Andrew, Sayeed, Eddy, Agans, Krystle N., Borisevich, Viktoriya, Cross, Robert W., Geisbert, Thomas W., Feinberg, Mark B., Gupta, Swati B., Parks, Christopher L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610558/ https://www.ncbi.nlm.nih.gov/pubmed/36298451 http://dx.doi.org/10.3390/vaccines10101582 |
Ejemplares similares
-
A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge
por: Woolsey, Courtney, et al.
Publicado: (2022) -
Durability of a Vesicular Stomatitis Virus-Based Marburg Virus Vaccine in Nonhuman Primates
por: Mire, Chad E., et al.
Publicado: (2014) -
Immune correlates of postexposure vaccine protection against Marburg virus
por: Woolsey, Courtney, et al.
Publicado: (2020) -
Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo)
por: Cross, Robert W, et al.
Publicado: (2018) -
Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates
por: Woolsey, Courtney, et al.
Publicado: (2018)