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Microstructure and Antibacterial Properties of Chitosan-Fe(3)O(4)-AgNP Nanocomposite

The goal of this research is to synthesize and characterize Fe(3)O(4)@Chitosan-AgNP nanocomposites in order to determine their antibacterial activity. The research methods include the synthesis of Fe(3)O(4)@Chitosan-AgNP nanocomposites, as well as the characterization of nanoparticles using scanning...

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Detalles Bibliográficos
Autores principales: Hartati, Hartati, Subaer, Subaer, Hasri, Hasri, Wibawa, Teguh, Hasriana, Hasriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610614/
https://www.ncbi.nlm.nih.gov/pubmed/36296842
http://dx.doi.org/10.3390/nano12203652
Descripción
Sumario:The goal of this research is to synthesize and characterize Fe(3)O(4)@Chitosan-AgNP nanocomposites in order to determine their antibacterial activity. The research methods include the synthesis of Fe(3)O(4)@Chitosan-AgNP nanocomposites, as well as the characterization of nanoparticles using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR) analysis, and subsequent antibacterial activity tests. The study’s findings demonstrated the successful synthesis of Fe(3)O(4)@Chitosan-AgNP nanocomposites, followed by nanoparticle characterization using SEM, TEM, XRD, and FTIR. Based on the XRD results, the conjugation of Fe(3)O(4)@Chitosan-AgNP nanocomposites has been successfully formed, as evidenced by the appearance of characteristic peaks of Fe(3)O(4), chitosan, and AgNPs. According to the FTIR results, the interaction between chitosan-AgNPs and conjugated Fe(3)O(4) occurred via the N atom in the NH(2) group and the O atom in the OH group, and C=O. The SEM and TEM images also show that the Fe(3)O(4)@Chitosan-AgNP conjugation is a nanoparticle-based composite material. The combination of nanocomposites Fe(3)O(4)@Chitosan-AgNPs has antibacterial activity, inhibiting the growth of bacteria such as Bacillus cereus and Escherichia coli.