Cargando…
The Anticancer Effect of a Flavonoid-Rich Extract of Bergamot Juice in THP-1 Cells Engages the SIRT2/AKT/p53 Pathway
Novel targets are constantly sought to fight hematologic malignancies. In this regard, high levels of SIRT2 expression are associated with unfavorable prognosis of acute myeloid leukemia. The interest in the plant kingdom has allowed the identification of ever-new anti-leukemic agents. Citrus × berg...
Autores principales: | Maugeri, Alessandro, Russo, Caterina, Musumeci, Laura, Lombardo, Giovanni Enrico, De Sarro, Giovambattista, Barreca, Davide, Cirmi, Santa, Navarra, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610715/ https://www.ncbi.nlm.nih.gov/pubmed/36297603 http://dx.doi.org/10.3390/pharmaceutics14102168 |
Ejemplares similares
-
The SIRT2 Pathway Is Involved in the Antiproliferative Effect of Flavanones in Human Leukemia Monocytic THP-1 Cells
por: Russo, Caterina, et al.
Publicado: (2022) -
Inflammation and Obesity: The Pharmacological Role of Flavonoids in the Zebrafish Model
por: Russo, Caterina, et al.
Publicado: (2023) -
Flavonoid Fraction of Bergamot Juice Reduces LPS-Induced Inflammatory Response through SIRT1-Mediated NF-κB Inhibition in THP-1 Monocytes
por: Risitano, Roberto, et al.
Publicado: (2014) -
A Flavonoid-Rich Extract of Mandarin Juice Counteracts 6-OHDA-Induced Oxidative Stress in SH-SY5Y Cells and Modulates Parkinson-Related Genes
por: Cirmi, Santa, et al.
Publicado: (2021) -
Mechanisms Underlying the Anti-Inflammatory Activity of Bergamot Essential Oil and Its Antinociceptive Effects †
por: Lombardo, Giovanni Enrico, et al.
Publicado: (2020)