Cargando…

Development and Evaluation of Novel Leflunomide SPION Bioemulsomes for the Intra-Articular Treatment of Arthritis

Systemic treatments for rheumatoid arthritis are associated with many side effects. This study aimed to minimize the side effects associated with the systemic administration of leflunomide (LEF) by formulating LEF-loaded emulsomes (EMLs) for intra-articular administration. Additionally, EMLs were lo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abbas, Haidy, Gad, Heba A., El Sayed, Nesrine S, Rashed, Laila Ahmed, Khattab, Mohamed A., Noor, Ahmad O., Zewail, Mariam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610779/ https://www.ncbi.nlm.nih.gov/pubmed/36297441 http://dx.doi.org/10.3390/pharmaceutics14102005

Ejemplares similares

Lipidic cubic-phase leflunomide nanoparticles (cubosomes) as a potential tool for breast cancer management
por: Zewail, Mariam, et al.
Publicado: (2022)

Rosmarinus officinalis L. hexane extract: phytochemical analysis, nanoencapsulation, and in silico, in vitro, and in vivo anti-photoaging potential evaluation
por: Ibrahim, Nehal, et al.
Publicado: (2022)

The Tragedy of Alzheimer’s Disease: Towards Better Management via Resveratrol-Loaded Oral Bilosomes
por: Abbas, Haidy, et al.
Publicado: (2021)

Neuroprotective Effect of Artichoke-Based Nanoformulation in Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways
por: El-Nashar, Heba A. S., et al.
Publicado: (2022)

Effect of intra-articular administration of superparamagnetic iron oxide nanoparticles (SPIONs) for MRI assessment of the cartilage barrier in a large animal model
por: Labens, Raphael, et al.
Publicado: (2017)

Homing and reparative effect of intra-articular injection of autologus mesenchymal stem cells in osteoarthritic animal model
por: Mokbel, Abir N, et al.
Publicado: (2011)

Reappraisal of the clinical use of leflunomide in rheumatoid arthritis and psoriatic arthritis
por: Jones, Peter BB, et al.
Publicado: (2010)

The Effect of Leflunomide on Cold and Vibratory Sensation in Patients with Rheumatoid Arthritis
por: Kim, Hyung Kuk, et al.
Publicado: (2012)

Leflunomide-induced and paraneoplastic ulcers in a rheumatoid arthritis patient
por: Vittori, Michael R., et al.
Publicado: (2022)

Intra-Articular Osteoid Osteoma Mimicking Juvenile Arthritis
por: Traore, Sidi Yaya, et al.
Publicado: (2014)

Intra-articular corticosteroid injections in juvenile idiopathic arthritis
por: Carrasco, Roberto, et al.
Publicado: (2014)

Spions as nano-theranostics agents
por: Zarepour, Atefeh, et al.
Publicado: (2017)

Evaluation of efficacy of combination of methotrexate and hydroxychloroquine with leflunomide in active rheumatoid arthritis
por: Shashikumar, N.S., et al.
Publicado: (2010)

Semiphysiologically Based Pharmacokinetic Model of Leflunomide Disposition in Rheumatoid Arthritis Patients
por: Hopkins, AM, et al.
Publicado: (2015)

Comparative Effectiveness of Tocilizumab with either Methotrexate or Leflunomide in the Treatment of Rheumatoid Arthritis
por: Narváez, Javier, et al.
Publicado: (2015)

Interleukin-18 in Brazilian Rheumatoid Arthritis Patients: Can Leflunomide Reduce It?
por: Gualberto Cardoso, Pablo Ramon, et al.
Publicado: (2021)

Combination of Methotrexate and Leflunomide Is Efficient and Safe for 60 Patients with Rheumatoid Arthritis
por: Chen, Fang, et al.
Publicado: (2022)

Reactive Arthritis Triggered by Adalimumab and Leflunomide in a Patient with Ankylosing Spondylitis
por: Liu, Ying, et al.
Publicado: (2022)

Nimesulide Improves the Symptomatic and Disease Modifying Effects of Leflunomide in Collagen Induced Arthritis
por: Al-Abd, Ahmed M., et al.
Publicado: (2014)

Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
por: Li, Sha, et al.
Publicado: (2022)

Development and optimization of curcumin analog nano-bilosomes using 2(1).3(1) full factorial design for anti-tumor profiles improvement in human hepatocellular carcinoma: in-vitro evaluation, in-vivo safety assay
por: Abbas, Haidy, et al.
Publicado: (2022)

PReS-FINAL-2048: Treatment with methotrexate plus leflunomide for juvenile idiopathic arthritis
por: Quesada-Masachs, E, et al.
Publicado: (2013)

Response to treatment with intra-articular triamcinolone hexacetonide and triamcinolone acetonide in oligo articular juvenile idiopathic arthritis
por: Harhay, Rana, et al.
Publicado: (2021)

Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
por: Uziel, Yosef, et al.
Publicado: (2008)

An intra-articular ganglion cyst in a patient with juvenile idiopathic arthritis
por: Deng, Donna Y, et al.
Publicado: (2014)

Septic arthritis of both knees following intra-articular injection of petrol
por: Janbakhsh, Alireza, et al.
Publicado: (2015)

Amelioration of experimentally induced inflammatory arthritis by intra-articular injection of visnagin
por: Gurram, Sowmyasree, et al.
Publicado: (2022)

Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management
por: Wen, Juan, et al.
Publicado: (2023)

An intra‐articular injectable phospholipids‐based gel for the treatment of rheumatoid arthritis
por: Yang, Yuping, et al.
Publicado: (2023)

Leflunomide-Induced Hidradenitis Suppurativa
por: Machan, Achraf, et al.
Publicado: (2020)

Leflunomide increases the risk of silent liver fibrosis in patients with rheumatoid arthritis receiving methotrexate
por: Lee, Sang-Won, et al.
Publicado: (2012)

Tripterygium Glycosides Combined with Leflunomide for Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
por: Yang, Yi-Jing, et al.
Publicado: (2020)

The prognostic value of whole-genome DNA methylation in response to Leflunomide in patients with Rheumatoid Arthritis
por: Chen, Yulan, et al.
Publicado: (2023)

Easy Synthesis and Characterization of Holmium-Doped SPIONs
por: Osial, Magdalena, et al.
Publicado: (2018)

Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release
por: Friedrich, Bernhard, et al.
Publicado: (2021)

Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits
por: Okura, Toshiyuki, et al.
Publicado: (2008)

Intra-articular corticosteroid therapy in oligoarticular juvenile arthritis: our clinical experience
por: Trigilia, C, et al.
Publicado: (2011)

Durability of response to intra-articular corticosteroid injections with triamcinolone hexacetonide in juvenile idiopathic arthritis
por: Srinivasan, Jaya, et al.
Publicado: (2012)

Surface Modification of SPIONs in PHBV Microspheres for Biomedical Applications
por: Idris, Maizlinda I., et al.
Publicado: (2018)

Poly ε-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model
por: Singh, Ekta, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ed3rccvn4p0plpgn9ohnmuke7r