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Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty

BACKGROUND: The most effective treatment for knee joint pain is total knee arthroplasty (TKA), but the risk of pain and swelling in patients after surgery is high. Ice application, ankle pump exercise and non-steroidal anti-inflammatory painkillers are the primary clinical treatments after surgery....

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Autores principales: Xing, Liang, Xu, Hui-Rong, Wang, Qing-Lin, Kong, Hua, Zhang, Hua, Tian, Jing, Ding, Ying, Yang, Ru-Xin, Zhang, Lei, Jiang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610864/
https://www.ncbi.nlm.nih.gov/pubmed/36312520
http://dx.doi.org/10.5312/wjo.v13.i10.932
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author Xing, Liang
Xu, Hui-Rong
Wang, Qing-Lin
Kong, Hua
Zhang, Hua
Tian, Jing
Ding, Ying
Yang, Ru-Xin
Zhang, Lei
Jiang, Bo
author_facet Xing, Liang
Xu, Hui-Rong
Wang, Qing-Lin
Kong, Hua
Zhang, Hua
Tian, Jing
Ding, Ying
Yang, Ru-Xin
Zhang, Lei
Jiang, Bo
author_sort Xing, Liang
collection PubMed
description BACKGROUND: The most effective treatment for knee joint pain is total knee arthroplasty (TKA), but the risk of pain and swelling in patients after surgery is high. Ice application, ankle pump exercise and non-steroidal anti-inflammatory painkillers are the primary clinical treatments after surgery. However, long-term use of non-steroidal anti-inflammatory pain relievers can easily cause gastrointestinal damage. Traditional Chinese medicine (TCM) ointments and tuina therapy integrate TCM and manipulation, which effectively promotes the penetration of TCM into the skin lesions, improves local blood circulation and inflammatory reaction and has good long-term effects on patients. AIM: To evaluate the efficacy of TCM ointment combined with tuina therapy in the treatment of pain and swelling after TKA. METHODS: The randomized controlled clinical trial enrolled 80 patients who underwent TKA via the same procedure. The patients were randomly divided among the treatment group (n = 40) and the control group (n = 40). The control group was given an analgesia pump in addition to oral painkillers as the postoperative intervention. The treatment group received TCM ointment with tuina therapy in addition to the analgesia pump and oral painkillers in the postoperative period. The following variables were recorded 3 d before surgery and 3 d, 7 d and 14 d after surgery: Visual analogue scale (VAS) score; skin temperature; circumferences at 15 cm above and below the patella; maximum active knee flexion angle; and the knee injury and Osteoarthritis Outcome score (KOOS). RESULTS: After treatment, VAS was significantly lower in the treatment group than the control group at 7 d (t = 7.536, P < 0.001) and 14 d (t = 8.563, P < 0.001). The skin temperature of participants in the treatment group was significantly lower than that in the control group at 7 d (t = 2.968, P = 0.004) and 14 d (t = 4.423, P < 0.001). The circumference values of the two positions in the treatment group were lower than those in the control group at 7 d [t = 2.315, P = 0.023 (above); t = 2.121, P = 0.037 (below)] and 14 d [t = 2.374, P = 0.020 (above); t = 2.095, P = 0.039 (below)]. After 14 d of treatment, the maximum active knee flexion angle and KOOS of the two groups were significantly improved but were significantly higher in the treatment group (P < 0.05 for both). CONCLUSION: TCM ointment and tuina therapy have significant advantages over standard care in the treatment of pain and swelling after TKA. This additional treatment may improve knee function but additional studies are needed to confirm our observations.
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spelling pubmed-96108642022-10-28 Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty Xing, Liang Xu, Hui-Rong Wang, Qing-Lin Kong, Hua Zhang, Hua Tian, Jing Ding, Ying Yang, Ru-Xin Zhang, Lei Jiang, Bo World J Orthop Clinical Trials Study BACKGROUND: The most effective treatment for knee joint pain is total knee arthroplasty (TKA), but the risk of pain and swelling in patients after surgery is high. Ice application, ankle pump exercise and non-steroidal anti-inflammatory painkillers are the primary clinical treatments after surgery. However, long-term use of non-steroidal anti-inflammatory pain relievers can easily cause gastrointestinal damage. Traditional Chinese medicine (TCM) ointments and tuina therapy integrate TCM and manipulation, which effectively promotes the penetration of TCM into the skin lesions, improves local blood circulation and inflammatory reaction and has good long-term effects on patients. AIM: To evaluate the efficacy of TCM ointment combined with tuina therapy in the treatment of pain and swelling after TKA. METHODS: The randomized controlled clinical trial enrolled 80 patients who underwent TKA via the same procedure. The patients were randomly divided among the treatment group (n = 40) and the control group (n = 40). The control group was given an analgesia pump in addition to oral painkillers as the postoperative intervention. The treatment group received TCM ointment with tuina therapy in addition to the analgesia pump and oral painkillers in the postoperative period. The following variables were recorded 3 d before surgery and 3 d, 7 d and 14 d after surgery: Visual analogue scale (VAS) score; skin temperature; circumferences at 15 cm above and below the patella; maximum active knee flexion angle; and the knee injury and Osteoarthritis Outcome score (KOOS). RESULTS: After treatment, VAS was significantly lower in the treatment group than the control group at 7 d (t = 7.536, P < 0.001) and 14 d (t = 8.563, P < 0.001). The skin temperature of participants in the treatment group was significantly lower than that in the control group at 7 d (t = 2.968, P = 0.004) and 14 d (t = 4.423, P < 0.001). The circumference values of the two positions in the treatment group were lower than those in the control group at 7 d [t = 2.315, P = 0.023 (above); t = 2.121, P = 0.037 (below)] and 14 d [t = 2.374, P = 0.020 (above); t = 2.095, P = 0.039 (below)]. After 14 d of treatment, the maximum active knee flexion angle and KOOS of the two groups were significantly improved but were significantly higher in the treatment group (P < 0.05 for both). CONCLUSION: TCM ointment and tuina therapy have significant advantages over standard care in the treatment of pain and swelling after TKA. This additional treatment may improve knee function but additional studies are needed to confirm our observations. Baishideng Publishing Group Inc 2022-10-18 /pmc/articles/PMC9610864/ /pubmed/36312520 http://dx.doi.org/10.5312/wjo.v13.i10.932 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Clinical Trials Study
Xing, Liang
Xu, Hui-Rong
Wang, Qing-Lin
Kong, Hua
Zhang, Hua
Tian, Jing
Ding, Ying
Yang, Ru-Xin
Zhang, Lei
Jiang, Bo
Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
title Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
title_full Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
title_fullStr Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
title_full_unstemmed Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
title_short Traditional Chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
title_sort traditional chinese medicine ointment combined with tuina therapy in treatment of pain and swelling after total knee arthroplasty
topic Clinical Trials Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610864/
https://www.ncbi.nlm.nih.gov/pubmed/36312520
http://dx.doi.org/10.5312/wjo.v13.i10.932
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