Cargando…

Cationic Perylene Antivirals with Aqueous Solubility for Studies In Vivo

Perylene-based compounds are attracting significant attention due to their high broad-spectrum antiviral activity against enveloped viruses. Despite unambiguous results of in vitro studies and high selectivity index, the poor water solubility of these compounds prevented in vivo evaluation of their...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shtro, Anna A., Garshinina, Anzhelika V., Alferova, Vera A., Kamzeeva, Polina N., Volok, Viktor P., Kolpakova, Ekaterina S., Nikitin, Timofei D., Chistov, Alexey A., Belyaev, Evgeny S., Korshun, Vladimir A., Kozlovskaya, Liubov I., Aralov, Andrey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610897/ https://www.ncbi.nlm.nih.gov/pubmed/36297288 http://dx.doi.org/10.3390/ph15101178

Ejemplares similares

Recent Advances in Molecular Mechanisms of Nucleoside Antivirals
por: Kamzeeva, Polina N., et al.
Publicado: (2023)

Hydrophobic Rose Bengal Derivatives Exhibit Submicromolar-to-Subnanomolar Activity against Enveloped Viruses
por: Rubekina, Anna A., et al.
Publicado: (2022)

Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses
por: Kozlovskaya, Liubov I., et al.
Publicado: (2021)

5-(Perylen-3-ylethynyl)uracil Derivatives Inhibit Reproduction of Respiratory Viruses
por: Nikolayeva, Y. V., et al.
Publicado: (2020)

Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Lipophilicity
por: Mikhnovets, Igor E., et al.
Publicado: (2023)

Ramified derivatives of 5-(perylen-3-ylethynyl)uracil-1-acetic acid and their antiviral properties
por: Sapozhnikova, Ksenia A., et al.
Publicado: (2019)

Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex
por: Ryazantsev, Dmitriy Y., et al.
Publicado: (2021)

Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation
por: Straková, Petra, et al.
Publicado: (2023)

Red light-emitting short Mango-based system enables tracking a mycobacterial small noncoding RNA in infected macrophages
por: Bychenko, Oksana S, et al.
Publicado: (2023)

Synthesis and Biological Evaluation of Benzo [4,5]- and Naphtho[2′,1′:4,5]imidazo[1,2-c]pyrimidinone Derivatives
por: Kamzeeva, Polina, et al.
Publicado: (2023)

Phenotypic Test of Benzo[4,5]imidazo[1,2-c]pyrimidinone-Based Nucleoside and Non-Nucleoside Derivatives against DNA and RNA Viruses, Including Coronaviruses
por: Kamzeeva, Polina, et al.
Publicado: (2023)

Nucleoside Analogs and Perylene Derivatives Modulate Phase Separation of SARS-CoV-2 N Protein and Genomic RNA In Vitro
por: Svetlova, Julia, et al.
Publicado: (2022)

Photosensitizing Antivirals
por: Mariewskaya, Kseniya A., et al.
Publicado: (2021)

New Inhibitors of Respiratory Syncytial Virus (RSV) Replication Based on Monoterpene-Substituted Arylcoumarins
por: Khomenko, Tatyana M., et al.
Publicado: (2023)

SARS-CoV-2 infection in children in Moscow in 2020: clinical features and impact on circulation of other respiratory viruses: SARS-CoV-2 infection in children in Moscow in 2020
por: Yakovlev, Alexander S., et al.
Publicado: (2022)

Antibiotics from Extremophilic Micromycetes
por: Baranova, A. A., et al.
Publicado: (2020)

Chemical Ecology of Streptomyces albidoflavus Strain A10 Associated with Carpenter Ant Camponotus vagus
por: Baranova, Anna A., et al.
Publicado: (2020)

Chemical Elicitors of Antibiotic Biosynthesis in Actinomycetes
por: Tyurin, Anton P., et al.
Publicado: (2018)

Development of a Promising Method for Producing Oligomeric Mixture of Branched Alkylene Guanidines to Improve Substance Quality and Evaluate Their Antiviral Activity against SARS-CoV-2
por: Shatalov, Denis O., et al.
Publicado: (2021)

Near-Infrared Dyes: Towards Broad-Spectrum Antivirals
por: Mariewskaya, Kseniya A., et al.
Publicado: (2022)

Modern Trends in Natural Antibiotic Discovery
por: Baranova, Anna A., et al.
Publicado: (2023)

Sensing of Antibiotic–Bacteria Interactions
por: Baranova, Anna A., et al.
Publicado: (2023)

Activity of Ingavirin (6-[2-(1H-Imidazol-4-yl)ethylamino]-5-oxo-hexanoic Acid) Against Human Respiratory Viruses in in Vivo Experiments
por: Zarubaev, Vladimir V., et al.
Publicado: (2011)

Membrane-Targeting Perylenylethynylphenols Inactivate Medically Important Coronaviruses via the Singlet Oxygen Photogeneration Mechanism
por: Mariewskaya, Kseniya A., et al.
Publicado: (2023)

Identification and Study of the Action Mechanism of Small Compound That Inhibits Replication of Respiratory Syncytial Virus
por: Shtro, Anna A., et al.
Publicado: (2023)

BN-Embedded Perylenes
por: Fang, Xiangdong
Publicado: (2021)

i-Clamp phenoxazine for the fine tuning of DNA i-motif stability
por: Tsvetkov, Vladimir B, et al.
Publicado: (2018)

Antifungal Activity of Amphiphilic Perylene Bisimides
por: Roa-Linares, Vicky C., et al.
Publicado: (2022)

New Analogues of Uridine as Possible Anti-Viral Agents Specific to SARS-CoV-2
por: Maslova, A. A., et al.
Publicado: (2022)

Evervac: phase I/II study of immunogenicity and safety of a new adjuvant-free TBE vaccine cultivated in Vero cell culture
por: Vorovitch, Mikhail F., et al.
Publicado: (2020)

Evaluation of the Antiviral Potential of Modified Heterocyclic Base and 5’-Norcarbocyclic Nucleoside Analogs Against SARS-CoV-2
por: Matyugina, E. S., et al.
Publicado: (2021)

Unwinding the SARS-CoV-2 Ribosomal Frameshifting Pseudoknot with LNA and G-Clamp-Modified Phosphorothioate Oligonucleotides Inhibits Viral Replication
por: Knizhnik, Ekaterina, et al.
Publicado: (2023)

Self-assembly behaviors of perylene- and naphthalene-crown macrocycle conjugates in aqueous medium
por: Shen, Xin, et al.
Publicado: (2019)

Self-sorted Oligophenylvinylene and Perylene Bisimide Hydrogels
por: Castilla, Ana M., et al.
Publicado: (2017)

Mechanoresponsive Self‐Assembled Perylene Bisimide Films
por: Adams, Victoria, et al.
Publicado: (2020)

Disappeared supramolecular isomer reappears with perylene guest
por: Park, In-Hyeok, et al.
Publicado: (2020)

Orbital Mapping of Semiconducting Perylenes on Cu(111)
por: Di Santo, Giovanni, et al.
Publicado: (2021)

Vitrification of octonary perylene mixtures with ultralow fragility
por: Hultmark, Sandra, et al.
Publicado: (2021)

Iridium and Ruthenium Complexes Bearing Perylene Ligands
por: Mauri, Luca, et al.
Publicado: (2022)

Experimental Assessment of Possible Factors Associated with Tick-Borne Encephalitis Vaccine Failure
por: Tuchynskaya, Ksenia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bpcam9o1mih0es4gbfa5hiaru0