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Sertaconazole-Nitrate-Loaded Leciplex for Treating Keratomycosis: Optimization Using D-Optimal Design and In Vitro, Ex Vivo, and In Vivo Studies
This study aims to develop efficient topical therapy for keratomycosis using sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to optimize STZN-loaded LP by utilizing soy phosphatidylcholine (SPC) molar ratio (X(1)), cationic surfactant molar ratio (X(2)), and cationic...
Autores principales: | Abdellatif, Menna M., Josef, Mina, El-Nabarawi, Mohamed A., Teaima, Mahmoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611087/ https://www.ncbi.nlm.nih.gov/pubmed/36297650 http://dx.doi.org/10.3390/pharmaceutics14102215 |
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