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Sertaconazole-Nitrate-Loaded Leciplex for Treating Keratomycosis: Optimization Using D-Optimal Design and In Vitro, Ex Vivo, and In Vivo Studies

This study aims to develop efficient topical therapy for keratomycosis using sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to optimize STZN-loaded LP by utilizing soy phosphatidylcholine (SPC) molar ratio (X(1)), cationic surfactant molar ratio (X(2)), and cationic...

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Detalles Bibliográficos
Autores principales: Abdellatif, Menna M., Josef, Mina, El-Nabarawi, Mohamed A., Teaima, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611087/
https://www.ncbi.nlm.nih.gov/pubmed/36297650
http://dx.doi.org/10.3390/pharmaceutics14102215

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