Metabolomic Study of Urine from Workers Exposed to Low Concentrations of Benzene by UHPLC-ESI-QToF-MS Reveals Potential Biomarkers Associated with Oxidative Stress and Genotoxicity

Benzene is a human carcinogen whose exposure to concentrations below 1 ppm (3.19 mg·m(−3)) is associated with myelotoxic effects. The determination of biomarkers such as trans-trans muconic acid (AttM) and S-phenylmercapturic acid (SPMA) show exposure without reflecting the toxic effects of benzene....

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Detalles Bibliográficos
Autores principales: Mendes, Michele P. R., Paiva, Maria José N., Costa-Amaral, Isabele C., Carvalho, Leandro V. B., Figueiredo, Victor O., Gonçalves, Eline S., Larentis, Ariane L., André, Leiliane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611274/
https://www.ncbi.nlm.nih.gov/pubmed/36295880
http://dx.doi.org/10.3390/metabo12100978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611274/
https://www.ncbi.nlm.nih.gov/pubmed/36295880
http://dx.doi.org/10.3390/metabo12100978

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