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Metabolomic Study of Urine from Workers Exposed to Low Concentrations of Benzene by UHPLC-ESI-QToF-MS Reveals Potential Biomarkers Associated with Oxidative Stress and Genotoxicity
Benzene is a human carcinogen whose exposure to concentrations below 1 ppm (3.19 mg·m(−3)) is associated with myelotoxic effects. The determination of biomarkers such as trans-trans muconic acid (AttM) and S-phenylmercapturic acid (SPMA) show exposure without reflecting the toxic effects of benzene....
Autores principales: | Mendes, Michele P. R., Paiva, Maria José N., Costa-Amaral, Isabele C., Carvalho, Leandro V. B., Figueiredo, Victor O., Gonçalves, Eline S., Larentis, Ariane L., André, Leiliane C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611274/ https://www.ncbi.nlm.nih.gov/pubmed/36295880 http://dx.doi.org/10.3390/metabo12100978 |
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