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Glycolytic Inhibitors Potentiated the Activity of Paclitaxel and Their Nanoencapsulation Increased Their Delivery in a Lung Cancer Model

Antiglycolytic agents inhibit cell metabolism and modify the tumor’s microenvironment, affecting chemotherapy resistance mechanisms. In this work, we studied the effect of the glycolytic inhibitors 3-bromopyruvate (3BP), dichloroacetate (DCA) and 2-deoxyglucose (2DG) on cancer cell properties and on...

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Detalles Bibliográficos
Autores principales:	Cunha, Andrea, Rocha, Ana Catarina, Barbosa, Flávia, Baião, Ana, Silva, Patrícia, Sarmento, Bruno, Queirós, Odília
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611291/ https://www.ncbi.nlm.nih.gov/pubmed/36297455 http://dx.doi.org/10.3390/pharmaceutics14102021

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