Cargando…

Autologous Genetically Enriched Leucoconcentrate in the Preventive and Acute Phases of Stroke Treatment in a Mini-Pig Model

The natural limitations of regeneration in the CNS are major problems for the treatment of neurological disorders, including ischaemic brain strokes. Among the approaches being actively developed to inhibit post-ischaemic negative consequences is the delivery of therapeutic genes encoding neuroprote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Safiullov, Zufar, Izmailov, Andrei, Sokolov, Mikhail, Markosyan, Vage, Kundakchan, Grayr, Garifulin, Ravil, Shmarov, Maksim, Naroditsky, Boris, Logunov, Denis, Islamov, Rustem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611398/ https://www.ncbi.nlm.nih.gov/pubmed/36297644 http://dx.doi.org/10.3390/pharmaceutics14102209

Ejemplares similares

New Therapy for Spinal Cord Injury: Autologous Genetically-Enriched Leucoconcentrate Integrated with Epidural Electrical Stimulation
por: Islamov, Rustem, et al.
Publicado: (2022)

Evaluation of the Autologous Genetically Enriched Leucoconcentrate on the Lumbar Spinal Cord Morpho-Functional Recovery in a Mini Pig with Thoracic Spine Contusion Injury
por: Garifulin, Ravil, et al.
Publicado: (2023)

Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model
por: Davleeva, Maria Aleksandrovna, et al.
Publicado: (2022)

Preventive Triple Gene Therapy Reduces the Negative Consequences of Ischemia-Induced Brain Injury after Modelling Stroke in a Rat
por: Markosyan, Vage, et al.
Publicado: (2020)

Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury
por: Islamov, Rustem R., et al.
Publicado: (2020)

Combined Supra- and Sub-Lesional Epidural Electrical Stimulation for Restoration of the Motor Functions after Spinal Cord Injury in Mini Pigs
por: Fadeev, Filip, et al.
Publicado: (2020)

Triple-Gene Therapy for Stroke: A Proof-of-Concept in Vivo Study in Rats
por: Sokolov, Mikhail E., et al.
Publicado: (2018)

Epidural Stimulation Combined with Triple Gene Therapy for Spinal Cord Injury Treatment
por: Islamov, Rustem, et al.
Publicado: (2020)

Evaluation of Direct and Cell-Mediated Lactoferrin Gene Therapy for the Maxillofacial Area Abscesses in Rats
por: Agatieva, Elima, et al.
Publicado: (2021)

Spinal Cord Molecular and Cellular Changes Induced by Adenoviral Vector- and Cell-Mediated Triple Gene Therapy after Severe Contusion
por: Izmailov, Andrei A., et al.
Publicado: (2017)

A Biosafety Study of Human Umbilical Cord Blood Mononuclear Cells Transduced with Adenoviral Vector Carrying Human Vascular Endothelial Growth Factor cDNA In Vitro
por: Salafutdinov, Ilnur I., et al.
Publicado: (2023)

Vaccination potential of B and T epitope-enriched NP and M2 against Influenza A viruses from different clades and hosts
por: Tutykhina, Irina, et al.
Publicado: (2018)

Combination of epidural electrical stimulation with ex vivo triple gene therapy for spinal cord injury: a proof of principle study
por: Fadeev, Filip Olegovich, et al.
Publicado: (2020)

Toll-Like Receptors (TLRs): The Role in Tumor Progression
por: Shcheblyakov, D.V., et al.
Publicado: (2010)

Triggering of Toll-like Receptor-2 in Mouse Myelomonocytic Leukaemia Cells WEHI-3B Leads to the Suppression of Apoptosis and Promotes Tumor Progression in Vivo
por: Shcheblyakov, D.V., et al.
Publicado: (2011)

The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector
por: Lebedeva, Ekaterina, et al.
Publicado: (2018)

An Efficient Method for the Delivery of the Interleukin-2 Gene to Human Hematopoietic Cells using the  Fiber-Modified Recombinant Adenovirus
por: Rogozhin, V.N., et al.
Publicado: (2011)

Chlamydial Type III Secretion System Needle Protein Induces Protective Immunity against Chlamydia muridarum Intravaginal Infection
por: Koroleva, Ekaterina A., et al.
Publicado: (2017)

Regulation of the Target Protein (Transgene) Expression in the Adenovirus Vector Using Agonists of Toll-Like Receptors
por: Bagaev, A. V., et al.
Publicado: (2014)

Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses
por: Tukhvatulin, Amir I., et al.
Publicado: (2016)

EVOLUTION AND EVALUATION OF AUTOLOGOUS MINI PUNCH GRAFTING IN VITILIGO
por: Lahiri, Koushik
Publicado: (2009)

A In Vitro and In Vivo Study of the Ability of NOD1 Ligands to Activate the Transcriptional Factor NF-kB
por: Tukhvatulin, A.I., et al.
Publicado: (2011)

Genetic Passive Immunization with Adenoviral Vector Expressing Chimeric Nanobody-Fc Molecules as Therapy for Genital Infection Caused by Mycoplasma hominis
por: Burmistrova, Daria A., et al.
Publicado: (2016)

Induction of a Protective Heterosubtypic Immune Response Against the Influenza Virus by using Recombinant Adenoviral Vectors Expressing Hemagglutinin of the Influenza H5 Virus
por: Shmarov, M.M., et al.
Publicado: (2010)

Autologous Platelet-rich Plasma Enriched Pixel Grafting
por: Bharathi Mohan, Padmalakshmi, et al.
Publicado: (2020)

Construction of a pIX-modified Adenovirus Vector Able to Effectively Bind to Nanoantibodies for Targeting
por: Garas, M. N., et al.
Publicado: (2014)

Association of Mycoplasma hominis infection with prostate cancer
por: Barykova, Yulia A., et al.
Publicado: (2011)

Autologous Antibody Capture to Enrich Immunogenic Viruses for Viral Discovery
por: Oude Munnink, Bas B., et al.
Publicado: (2013)

Autologous Mini Punch Grafting: An Experience of Using Motorized Power Punch in 10 Patients
por: Chandrashekar, BS, et al.
Publicado: (2014)

Immunogenicity of Different Forms of Middle East Respiratory Syndrome S Glycoprotein
por: Ozharovskaia, T. A., et al.
Publicado: (2019)

NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo
por: Tukhvatulin, Amir I, et al.
Publicado: (2020)

Newton-type methods for optimization and variational problems
por: Izmailov, Alexey F, et al.
Publicado: (2014)

Enhanced Hydrogen Generation from Magnesium–Aluminum Scrap Ball Milled with Low Melting Point Solder Alloy
por: Buryakovskaya, Olesya A., et al.
Publicado: (2023)

Effects of Bi–Sn–Pb Alloy and Ball-Milling Duration on the Reactivity of Magnesium–Aluminum Waste-Based Materials for Hydrogen Production
por: Buryakovskaya, Olesya A., et al.
Publicado: (2023)

The Effect of Mesenchymal Stem Cell-Enriched Scaffolds on MMP-8 and TGF-β Levels of Vertebrae Postlaminoplasty in Rabbit Model
por: Rahyussalim, Ahmad Jabir, et al.
Publicado: (2021)

Transverse Needling After Autologous Mini-Punch Grafts Improves Repigmentation in Stable Non-Segmental Vitiligo
por: Ragab, Magdy, et al.
Publicado: (2021)

Effective Genetic Expression of Nanoantibodies by Recombinant Adenoviral Vector in vitro
por: Gribova, I.Yu., et al.
Publicado: (2011)

Arthroscopy versus mini-arthrotomy approach for matrix-induced autologous chondrocyte implantation in the knee: a systematic review
por: Migliorini, Filippo, et al.
Publicado: (2021)

A mini-pig model for evaluating the efficacy of autologous platelet patches on induced acute full thickness wound healing
por: Tsai, Hsin-Chung, et al.
Publicado: (2019)

Protective Immune Response against Bacillus anthracis Induced by Intranasal Introduction of a Recombinant Adenovirus Expressing the Protective Antigen Fused to the Fc-fragment of IgG2a
por: Shcherbinin, D. N., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_n9aieng72erj3lsv6pof4t6uaa